ID A0A0M8T1S6_9ACTN Unreviewed; 427 AA.
AC A0A0M8T1S6;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Inter-alpha-trypsin inhibitor heavy chain H5 {ECO:0000313|EMBL:KOU47714.1};
GN ORFNames=ADK54_12475 {ECO:0000313|EMBL:KOU47714.1};
OS Streptomyces sp. WM6378.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415557 {ECO:0000313|EMBL:KOU47714.1, ECO:0000313|Proteomes:UP000037774};
RN [1] {ECO:0000313|Proteomes:UP000037774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6378 {ECO:0000313|Proteomes:UP000037774};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU47714.1}.
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DR EMBL; LGDD01000120; KOU47714.1; -; Genomic_DNA.
DR RefSeq; WP_053725653.1; NZ_LGDD01000120.1.
DR AlphaFoldDB; A0A0M8T1S6; -.
DR PATRIC; fig|1415557.3.peg.2789; -.
DR OrthoDB; 4318225at2; -.
DR Proteomes; UP000037774; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..427
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005823433"
FT TRANSMEM 395..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..234
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 427 AA; 44844 MW; 9F930BAD0C8AF48A CRC64;
MITRKRLAAG VCALVATFAT GILPAAGTAS AAVAPDGQSE QAAPKVDLVL DVSGSMRTAD
IDGKSRMSAA KQAFNEVLDS VPQEVQLGIR TLGANYPGED RKVGCKDTRA LYPVGPLNRT
EAKTAVATLA PTGWTPIGPA LQGAAEDLKG GDATRRIVLI TDGEDTCQPL DPCEVARDIA
AQGIHLTIDT LGLIPDAKTR EQLTCIAEAT GGTYTSVQHT DQLSGKVKQL VDRAADPVAV
PVATTGTASC ENAPQLKPGL YTDREKFAEH RSYKVDVKPG QELRASASIG VDRQTNPDYG
VLLRAVTAHG REIVRGSEAG DGRTDLISTG LRYPKAPADD SDDKTPETVC LQVSNSFSAP
PGVKTDPGLP VELAIDVVDG PDHASDVASF GLGRGWWLLG ALALTGLVAG LVWGWISRWR
IAVWRTN
//
