ID A0A0M8TKU8_9ACTN Unreviewed; 359 AA.
AC A0A0M8TKU8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:KOU63549.1};
GN ORFNames=ADK57_22230 {ECO:0000313|EMBL:KOU63549.1};
OS Streptomyces sp. MMG1533.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415546 {ECO:0000313|EMBL:KOU63549.1, ECO:0000313|Proteomes:UP000037741};
RN [1] {ECO:0000313|Proteomes:UP000037741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1533 {ECO:0000313|Proteomes:UP000037741};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU63549.1}.
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DR EMBL; LGDG01000213; KOU63549.1; -; Genomic_DNA.
DR RefSeq; WP_053751252.1; NZ_LGDG01000213.1.
DR AlphaFoldDB; A0A0M8TKU8; -.
DR STRING; 1415546.ADK57_22230; -.
DR PATRIC; fig|1415546.3.peg.4818; -.
DR OrthoDB; 9785139at2; -.
DR Proteomes; UP000037741; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01574; PBP1_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 20..74
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 359 AA; 37624 MW; 66308162E37633FA CRC64;
MQEAIDAPRS GGGPQAPKTV SIRDVAKEAG VSHQTVSRVV NGHPRVKEST RARVLDVIAE
LGYTPNRMAR ALAGGAVRSV TVLTSDTSLY GASATLKGIE EAARAADFAV GISVLDAGSA
QQPADVAARV SRPGEAVLVI AFDAAGVRAW QALPAGFPAA AAVERPEDGR PGDRPQLWLD
DRAAAAQATR YLIGLGHETV HYLAIPSSTT RIGQRAEGWR DALRTAGKPL PEPIDAGWSP
RSGYLVARSL LADPSVTAVL CGNDDLALGV LRAAREAGRD VPGDLSVVGF DDAPHSAYAH
PALTTVRLDF EGLGRGCFGL LHRLLEPDTA PALPLWAEPE LIVRESSGPA PLRRDRPQG
//
