ID A0A0M8TQW8_9ACTN Unreviewed; 306 AA.
AC A0A0M8TQW8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:KOU63455.1};
GN ORFNames=ADK57_21540 {ECO:0000313|EMBL:KOU63455.1};
OS Streptomyces sp. MMG1533.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415546 {ECO:0000313|EMBL:KOU63455.1, ECO:0000313|Proteomes:UP000037741};
RN [1] {ECO:0000313|Proteomes:UP000037741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1533 {ECO:0000313|Proteomes:UP000037741};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU63455.1}.
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DR EMBL; LGDG01000213; KOU63455.1; -; Genomic_DNA.
DR RefSeq; WP_053751127.1; NZ_LGDG01000213.1.
DR AlphaFoldDB; A0A0M8TQW8; -.
DR STRING; 1415546.ADK57_21540; -.
DR PATRIC; fig|1415546.3.peg.4663; -.
DR OrthoDB; 3727682at2; -.
DR Proteomes; UP000037741; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd05289; MDR_like_2; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR PANTHER; PTHR44154; QUINONE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR44154:SF1; QUINONE OXIDOREDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037741};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 11..302
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 306 AA; 31240 MW; A621CF6FCE84E7CF CRC64;
MPKAVAIHDF GGPDVLGLID IPDPVPGPGQ VTVRVRAAGV NGFDCRVRSG GMRGRYPVEF
PQILGNEFAG VVERTGPEVT GFAPGDEVLG FAVLQSGAEV LAVGADQITA KPPGLSWEVA
GSLSAVGQTA DIALTELRVG KGDTVLVHAA AGGVGSLAVQ LVRERGGTAI GSASERNHDY
LRSLGVLPVA YGPGFADRVR ALAPDGIDAA LDCHGGPEAL AVSLELVADR ARIGTIANFR
AAAQEGIVMP QVVRSASRLA ALAALCADGS LQPHIDAVFP FAEAAAAHRT LEQGHVRGKL
VLVPAL
//
