ID A0A0M8TSJ9_9ACTN Unreviewed; 335 AA.
AC A0A0M8TSJ9;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KOU73782.1};
GN ORFNames=ADK57_08445 {ECO:0000313|EMBL:KOU73782.1};
OS Streptomyces sp. MMG1533.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415546 {ECO:0000313|EMBL:KOU73782.1, ECO:0000313|Proteomes:UP000037741};
RN [1] {ECO:0000313|Proteomes:UP000037741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1533 {ECO:0000313|Proteomes:UP000037741};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU73782.1}.
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DR EMBL; LGDG01000044; KOU73782.1; -; Genomic_DNA.
DR RefSeq; WP_053748745.1; NZ_LGDG01000044.1.
DR AlphaFoldDB; A0A0M8TSJ9; -.
DR STRING; 1415546.ADK57_08445; -.
DR PATRIC; fig|1415546.3.peg.1839; -.
DR OrthoDB; 59108at2; -.
DR Proteomes; UP000037741; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..58
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 335 AA; 35761 MW; FAD19D54B71AD871 CRC64;
MRPPTIRDVA DRAGVSKSLV SLVLRGSEQV RPEKRDAVLR AVRELGYRPN AAARSLSEQR
TRTVGVLLND LRNPWFVDLL DGLNPLLHEH GLHMLLGDAR LNRRTGQDLA RPFLDLQADG
LVVVGTLPDP AALEAVAERI PVVVAGAREP VPPGVDVVAG DDERGARLVT EHLIGLGHRR
IAHIAGYGAV GELRRASFES VMRAHGLADT ALVEPGDLTE EGGFRAAVRL LGRPGRPTAV
VAVNDITAVG VLSAAAELGL RVPHDVSVTG YDDTSISRLR HLWLTTVDNA GHEVGRRAAR
CLLDRFEGAG GAGRLHLAAP ALEIRGTTAA PPLRD
//
