ID A0A0M8UUN3_9ACTN Unreviewed; 537 AA.
AC A0A0M8UUN3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=FAD-linked oxidase {ECO:0000313|EMBL:KOV51037.1};
GN ORFNames=ADL00_41505 {ECO:0000313|EMBL:KOV51037.1};
OS Streptomyces sp. AS58.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519489 {ECO:0000313|EMBL:KOV51037.1, ECO:0000313|Proteomes:UP000037758};
RN [1] {ECO:0000313|EMBL:KOV51037.1, ECO:0000313|Proteomes:UP000037758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AS58 {ECO:0000313|EMBL:KOV51037.1,
RC ECO:0000313|Proteomes:UP000037758};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR625650-3};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV51037.1}.
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DR EMBL; LGDU01000403; KOV51037.1; -; Genomic_DNA.
DR RefSeq; WP_053763470.1; NZ_LGDU01000403.1.
DR AlphaFoldDB; A0A0M8UUN3; -.
DR PATRIC; fig|1519489.3.peg.9340; -.
DR OrthoDB; 9811557at2; -.
DR Proteomes; UP000037758; Unassembled WGS sequence.
DR GO; GO:0005777; C:peroxisome; IEA:UniProt.
DR GO; GO:0008609; F:alkylglycerone-phosphate synthase activity; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.30.300.330; -; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR InterPro; IPR025650; Alkyl-DHAP_Synthase.
DR InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR PANTHER; PTHR46568; ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL; 1.
DR PANTHER; PTHR46568:SF1; ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL; 1.
DR Pfam; PF02913; FAD-oxidase_C; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR625650-3};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR625650-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000037758}.
FT DOMAIN 90..271
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
FT REGION 352..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 455
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625650-1"
FT BINDING 255..261
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR625650-3"
FT BINDING 394
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR625650-2"
FT SITE 306
FT /note="Important for enzyme activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR625650-4"
SQ SEQUENCE 537 AA; 57348 MW; C3281425D7D04D75 CRC64;
MTRSWWGWGN VEDEIRGAEL DTLLDRVRAL VPGELAGHEP PDVAALGLPE PRVSAPASLA
ALCSADPGDR AAHAHGKAFR DVVRNLHGDL RHVPDLVARP RDERDVVDLL DWCTREGIAV
IAFGGGSSVV GGVEPRCSDD RPVVTVDLGR LNRVLEVDVT SRAARVQAGV FGPHLEEQLA
PHDLTLRHFP QSFEFSTLGG WLATRAGGHY ATLYTHIDDL VQSIRAVTPI GVSESRRLPG
SGAGPSPDRL LLGSEGTLGV ITEAWMRLQR RPRWRARTSV RFADHAAAVA ATRAVAQSGL
NPANCRLLDA AEALIHAGVN APGGVLVLGF ESADHPVRDR LERALELCRD HGGVPSAERG
GNGGDGTGGT GGTAGGDAVG DTWRASFLRM PYQRDALARH AMIAETFETA CTWDRFDELH
HAVTEAARQA MHKVTGTGVV TCRFTHVYPD GPAPYYGIYA PGRWGSTVAQ WDDIKAAVSE
AIATHGGTIT HHHAVGRDHR PWYDRQRPAP FATALTAAKT ALDPAGILNP GVLLAAG
//
