ID A0A0M8V582_9ACTN Unreviewed; 1059 AA.
AC A0A0M8V582;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Tetratricopeptide repeat protein {ECO:0000313|EMBL:KOV59071.1};
GN ORFNames=ADL01_36170 {ECO:0000313|EMBL:KOV59071.1};
OS Streptomyces sp. NRRL WC-3618.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519490 {ECO:0000313|EMBL:KOV59071.1, ECO:0000313|Proteomes:UP000037738};
RN [1] {ECO:0000313|EMBL:KOV59071.1, ECO:0000313|Proteomes:UP000037738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL WC-3618 {ECO:0000313|EMBL:KOV59071.1,
RC ECO:0000313|Proteomes:UP000037738};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV59071.1}.
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DR EMBL; LGDW01000473; KOV59071.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8V582; -.
DR PATRIC; fig|1519490.3.peg.7888; -.
DR Proteomes; UP000037738; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 3.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 7.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000037738};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 1..93
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT REPEAT 769..802
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DNA_BIND 1..93
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 248..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1059 AA; 115547 MW; E76D9F1371FC3FFE CRC64;
MDVRLLGPVE VMSGGRRVPL HGAKPTAILA ALVVHLGEVL SVERLVELTW EEEPPATARA
LVASHVSGLR RALAGTEGGD AIRTRSPGYV AEFPPSAVDA RRFEEAFAAG RSAALDGRAE
EAVDTLRAAS GLWRGPNALE GLGQSFARVE AMRLAELRLE AKEFRFSAEL DLDRRTDLVA
ELVAHVAAHP LRERPRGQLM TALYRAGRLP DALRCYDEGR RLLRTELGVD PGPDLRALHQ
ALLRADPTVL GAPARRKGTA SGKRPDRPAP MEAAAASRAD ANTPSPHRPE QPHDDTTRPA
PSQLPPDVAD FVGRTEQIAW ATSLLEQVRN PLRTAPPIGV ISGRSGTGKT ALAVHVGHRV
AALFPDGQLF VDLRASDSEP VRTVDALARL LRALGVDPET PGHDEEDLLG LYRTHIAHRR
VLLILDNAVS EALLRPLLPP GGGSAVLITG RRRLVALEGA AHLDLGVPSQ TEALDLLARV
AGPTRPALEP DRAAEIVALC GRLPLAVRVA GVRLAARPHW TPARLASRLR DERRRLDELQ
AGDLEVRASL GLGYADLDLQ QRRALRRLAL MDLPDFAAWV AGPLLDVSED DADDAVEQLV
DCHFVEVVGT DETGRTRYRI HDLAREYARE RCLADETRQE RETAVRRLVD RWLVMARSAA
AHGPGGASRL LPVTTTDEPV PAAAQLTPPT KPLTDLTGEP AAWFAAEQRC LLAGVAHCAE
HGMFDAARDL AATLMAASAA LYNQFDAWSR SHDVALEAVR RGGDVEGEAR LLNGLGQLRL
EQDRFDEAYA FFAAALGLFE KRSVRSGSAD ALAGMGAARR EQARFDEALT LLTSALERYR
EPEDIAPMAH VLYGIGSVHR EQGRDDDAWE ALSRAHRLYV TAWDRHGEAL ALRSLGLCHR
ARGDLPAAET LLRQALGLFE ETGDAFGVMY ASQSLAKVEL RQGRMAEARR RLDRCLETTR
ERQDMFGEAL VLRTLGEWCL AASDWETATD TLRQALALWD KLELPLWRAR TLRDLSRAAL
ARGAADTARE LEEEAYGVFQ RLGSREALEL PEPRDVPGH
//
