ID A0A0M8VLR5_9ACTN Unreviewed; 929 AA.
AC A0A0M8VLR5;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:KOV65363.1};
GN ORFNames=ADL00_19495 {ECO:0000313|EMBL:KOV65363.1};
OS Streptomyces sp. AS58.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519489 {ECO:0000313|EMBL:KOV65363.1, ECO:0000313|Proteomes:UP000037758};
RN [1] {ECO:0000313|EMBL:KOV65363.1, ECO:0000313|Proteomes:UP000037758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AS58 {ECO:0000313|EMBL:KOV65363.1,
RC ECO:0000313|Proteomes:UP000037758};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV65363.1}.
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DR EMBL; LGDU01000197; KOV65363.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8VLR5; -.
DR PATRIC; fig|1519489.3.peg.4419; -.
DR Proteomes; UP000037758; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR45832; SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED; 1.
DR PANTHER; PTHR45832:SF25; SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KOV65363.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000037758};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:KOV65363.1};
KW Transferase {ECO:0000313|EMBL:KOV65363.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 694..715
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..628
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 71..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 307..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 723..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..687
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..776
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 929 AA; 96175 MW; F742A890137C2967 CRC64;
MTSRAAGGGN VEDYAGRVLA DRYRLPLPPS DEYELTETRA FDTYSGQEVL VRQVPLPEVV
EAEVLDAEGL PDGFTARDRG ARRTPAPRAG TRRPTDPAVR RAVEAAQAAA RIPDHPRLDQ
VFDVFAEGGS LWIVSEWVAS RPLAALLAEQ PLTPYRAAEV ASDVLTALRV LHAHGWVHRN
ITARTVLVCD DGRVMLTGLA VGAAEEALCG YDPVPEWMYG ADEGGGAADP GGRPGSGGGS
AASGATGAAG GAGAAIGPGT TFGPGGAIAA RGAVAPGGSR GAGVPGGVGG GDPEAARRAA
IEARAARGLP LPGGSGVHTP GGSAVPARRA QETGGDIRAQ RAGAIAAYRA GARAAARVQE
AQQSGRAALP EARSGSEGAG AQSPYTSGQA EQQTGRPALP GARPASEGGA EQPYAPGAGR
LHTPDGAPPG QIADPYGVRG TPWPGGAAST DRYGQGALHG DGLARQGAPA PGHGTAVPTD
RTALPSGGTD PVPAPSSWDD LVAGTPVARR GPTTALAAER ARQARMAVVG PVTERWAPEQ
AGPVHENWRL APPIGPSTDL WALGALLFRA VQGHAPYPEE STAELVQMVC AEPPAFAEEC
GPLRPVVESL LRQDPTERLD FEELRGWLRS LVRSAPEPEA GVHVVAAPPA DASRLPIVRR
KGELVRRRRA GLPAAHGRHK RDRHKQKTGS PRSLGRTLLV LVLLAMAGAI AYAVLFMPKA
GEGGGGAGGP ERTGAAGQVG NAPERTPEAS SEPRPDQNAS GEPAESAGST EAQTDAPQVA
DGFELRTDPE GFRVAVAEGW QRTPEKGNGR VVYGKGDFEL IVVPGRDGAD EYGGDPMTYQ
REREPELLPY RESSWATSTG LKTIEVGGRT MAEGQFTWTG EGGGELFVRN LAMLVDGRYH
VVQLRGPESE RDEVTRLYEQ AAATYRATG
//
