ID A0A0M8W6G0_9ACTN Unreviewed; 349 AA.
AC A0A0M8W6G0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=2-dehydropantoate 2-reductase {ECO:0000313|EMBL:KOV79470.1};
GN ORFNames=ADL01_13280 {ECO:0000313|EMBL:KOV79470.1};
OS Streptomyces sp. NRRL WC-3618.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519490 {ECO:0000313|EMBL:KOV79470.1, ECO:0000313|Proteomes:UP000037738};
RN [1] {ECO:0000313|EMBL:KOV79470.1, ECO:0000313|Proteomes:UP000037738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL WC-3618 {ECO:0000313|EMBL:KOV79470.1,
RC ECO:0000313|Proteomes:UP000037738};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV79470.1}.
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DR EMBL; LGDW01000107; KOV79470.1; -; Genomic_DNA.
DR RefSeq; WP_053742159.1; NZ_LGDW01000107.1.
DR AlphaFoldDB; A0A0M8W6G0; -.
DR PATRIC; fig|1519490.3.peg.2913; -.
DR OrthoDB; 9796561at2; -.
DR Proteomes; UP000037738; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR21708:SF26; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037738}.
FT DOMAIN 4..148
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 189..310
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
FT REGION 254..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 349 AA; 36543 MW; 37C5F7A3082D4681 CRC64;
MRYIIIGAGA VGGAIGGRLA GAGHDVVLVA RGAQYEALRA HGLRLVTPDG THTYRLPTVD
GPAGLGELRA DDVLVLAVKT QDSEAALAAW GPAPVEGGGT AAERLPLLCA QNGVESPRLA
LRRFRRVYGV CVWLPAAYEE PGVVSAAGAP LTGILFLGRH PHGTDDTVRR IAADLEQTAA
FEAPVVPDVA RWQYAKLLTN LGNAIRALSG AADSVDSERL RERVYAEGES VLAAAGIPYA
SAAEAKERRG DKITLRPLPG TEPGGGSSWQ SLSRGTGTIE TDYLNGEIAL LGRLYGVPTP
LNELLQRLAN TFARERRPAG SLPSAELVRL ADEAVAAVTF VAEPSSGRL
//
