ID A0A0M8WCM2_9NOCA Unreviewed; 490 AA.
AC A0A0M8WCM2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Catalase {ECO:0000313|EMBL:KOV83259.1};
GN ORFNames=ADL03_20730 {ECO:0000313|EMBL:KOV83259.1};
OS Nocardia sp. NRRL S-836.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1519492 {ECO:0000313|EMBL:KOV83259.1, ECO:0000313|Proteomes:UP000037746};
RN [1] {ECO:0000313|Proteomes:UP000037746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-836 {ECO:0000313|Proteomes:UP000037746};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|PIRSR:PIRSR038928-2};
CC -!- SIMILARITY: Belongs to the catalase family.
CC {ECO:0000256|ARBA:ARBA00005329}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV83259.1}.
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DR EMBL; LGDY01000101; KOV83259.1; -; Genomic_DNA.
DR RefSeq; WP_053735139.1; NZ_LGDY01000101.1.
DR AlphaFoldDB; A0A0M8WCM2; -.
DR STRING; 1519492.ADL03_20730; -.
DR PATRIC; fig|1519492.3.peg.4447; -.
DR OrthoDB; 3169619at2; -.
DR Proteomes; UP000037746; Unassembled WGS sequence.
DR GO; GO:0004096; F:catalase activity; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd08156; catalase_clade_3; 1.
DR Gene3D; 2.40.180.10; Catalase core domain; 1.
DR InterPro; IPR018028; Catalase.
DR InterPro; IPR040333; Catalase_3.
DR InterPro; IPR024708; Catalase_AS.
DR InterPro; IPR024711; Catalase_clade1/3.
DR InterPro; IPR011614; Catalase_core.
DR InterPro; IPR010582; Catalase_immune_responsive.
DR InterPro; IPR020835; Catalase_sf.
DR PANTHER; PTHR11465; CATALASE; 1.
DR PANTHER; PTHR11465:SF61; CATALASE; 1.
DR Pfam; PF00199; Catalase; 1.
DR Pfam; PF06628; Catalase-rel; 1.
DR PIRSF; PIRSF038928; Catalase_clade1-3; 1.
DR PRINTS; PR00067; CATALASE.
DR SMART; SM01060; Catalase; 1.
DR SUPFAM; SSF56634; Heme-dependent catalase-like; 1.
DR PROSITE; PS00438; CATALASE_2; 1.
DR PROSITE; PS51402; CATALASE_3; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR038928-2};
KW Hydrogen peroxide {ECO:0000256|ARBA:ARBA00023324};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR038928-2};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR038928-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559};
KW Reference proteome {ECO:0000313|Proteomes:UP000037746}.
FT DOMAIN 11..397
FT /note="Catalase core"
FT /evidence="ECO:0000259|SMART:SM01060"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 58
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT ACT_SITE 131
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT BINDING 341
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-2"
SQ SEQUENCE 490 AA; 54811 MW; 5961586C248645A4 CRC64;
MAFEDNTDPL TTAAGAPVAD NQNSLTAGPR GPVLLQDLWL LEKLAHFDRE VIPERRMHAK
GSGAFGTFTV TADLTAYTGA ALFGAVGNRC ETFVRFSTVA GERGAADAER DIRGFAVRFY
TAEGNWDVVG NNTPVFFFRD PLKFPDLARA VKRDPRTNLR DPENNWGFWT NLPEALHQVT
IVMSDRGIPR SYRHMHGFGS HTYSMINADG VRHWVKFHFR TEQGVENLTD EQAGALIGRD
RESHQRDLYD AIERGEFPAW KLYLQVMPEA DAAHYRFHPF DLTKVWSKED YPLVEAGELR
LHRNPDNYFA DVEQVAFTPA NVVPGISLSP DRMLQGRLFS YGDAARYRLG VNHHQIPVNH
PSGARLVNTY HRDGAMRVDG NQGGVPGIEP NNSGRWAEQP AYAEPAQAVG AAADRFDFRA
DDDNYYEQPG DLFRLMTAEQ QQALFDNTAR AIRGARPQTV ERHIAHCAKA DPAYGEGVRK
ACEAIGALWV
//
