ID A0A0M8XAS2_9ACTN Unreviewed; 353 AA.
AC A0A0M8XAS2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KOX02409.1};
GN ORFNames=ADL04_12215 {ECO:0000313|EMBL:KOX02409.1};
OS Streptomyces sp. NRRL B-3648.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519493 {ECO:0000313|EMBL:KOX02409.1, ECO:0000313|Proteomes:UP000037702};
RN [1] {ECO:0000313|EMBL:KOX02409.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-3648 {ECO:0000313|EMBL:KOX02409.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOX02409.1}.
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DR EMBL; LGDZ01000119; KOX02409.1; -; Genomic_DNA.
DR RefSeq; WP_053708736.1; NZ_LGDZ01000119.1.
DR AlphaFoldDB; A0A0M8XAS2; -.
DR PATRIC; fig|1519493.3.peg.2615; -.
DR OrthoDB; 1938857at2; -.
DR Proteomes; UP000037702; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037702};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 11..65
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 353 AA; 37493 MW; 4D1B508D8FF07C0E CRC64;
MPKRRSPARR PTMKDIARRA GVSESAVSFA LNGRPGVSEA TRARVRRVAE QLGWRPSTAA
RALSGEGAAT VGFVLARPAH TLGVDSFFLQ LVSGIQEVLA ERHLGLLFQV AQDVTDECVV
YRRWWAEHRV DGVLVADPRA DDPRPGLLDE LGLPAVVIGG APDERHPGLS TVWADDAGAM
ASVVDELTAL GHRRIVHIAG LPDLAHTRRR TATLRAEAER RGLTEVRSVT TDYSDTQGAA
VTRRVLNSPA PPTALIYDND VMAVAGVSAA AGLGCRVPED VSVVSWEDSA LCRMVTPRLS
ALSRDSAEFG RTAARELLSL LDGAPARAVG VPVPRLTGRG STAAVRAPGG RVS
//
