ID A0A0M8Y4U1_9PSEU Unreviewed; 275 AA.
AC A0A0M8Y4U1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=MerR family transcriptional regulator {ECO:0000313|EMBL:KOX17421.1};
GN ORFNames=ADK67_38295 {ECO:0000313|EMBL:KOX17421.1};
OS Saccharothrix sp. NRRL B-16348.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1415542 {ECO:0000313|EMBL:KOX17421.1, ECO:0000313|Proteomes:UP000037722};
RN [1] {ECO:0000313|EMBL:KOX17421.1, ECO:0000313|Proteomes:UP000037722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16348 {ECO:0000313|EMBL:KOX17421.1,
RC ECO:0000313|Proteomes:UP000037722};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOX17421.1}.
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DR EMBL; LGED01000241; KOX17421.1; -; Genomic_DNA.
DR RefSeq; WP_053721451.1; NZ_LGED01000241.1.
DR AlphaFoldDB; A0A0M8Y4U1; -.
DR STRING; 1415542.ADK67_38295; -.
DR PATRIC; fig|1415542.3.peg.8252; -.
DR OrthoDB; 9809391at2; -.
DR Proteomes; UP000037722; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd01106; HTH_TipAL-Mta; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 1.10.490.50; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036244; TipA-like_antibiotic-bd.
DR InterPro; IPR012925; TipAS_dom.
DR PANTHER; PTHR30204:SF90; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TIPA; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF13411; MerR_1; 1.
DR Pfam; PF07739; TipAS; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF89082; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 17..86
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
SQ SEQUENCE 275 AA; 30392 MW; 0F1DDFF962EA3243 CRC64;
MPDAVTDAAN AAADADGLTV GEVSTRLGVT IRALHHWDEI GLARPSLRTA AGYRLYTSGD
LERLHRIVVY RELGLGLDRI RAVLDDPTAN VPAALREQRT QVTERIERLR QLGTGLDRMI
DAHERGLLLT AEQQAAIFGP DWNPDWSAQA RQRYGDTTQW LQYAERSAAR GPEEWQAIAD
TVTKLDRALA DAMDAGVAPG SPEANALAES HREVFSSYFP LTREMQVCLG RMFETDPGYA
AHYNGIRAGL ATWFRRVIDA NACAHGIDPD TAKWQ
//
