ID   A0A0M9DUW5_9BACT        Unreviewed;       937 AA.
AC   A0A0M9DUW5;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=type I site-specific deoxyribonuclease {ECO:0000256|ARBA:ARBA00012654};
DE            EC=3.1.21.3 {ECO:0000256|ARBA:ARBA00012654};
GN   ORFNames=AD998_18190 {ECO:0000313|EMBL:KOY87806.1};
OS   bacterium 336/3.
OC   Bacteria.
OX   NCBI_TaxID=1664068 {ECO:0000313|EMBL:KOY87806.1, ECO:0000313|Proteomes:UP000037950};
RN   [1] {ECO:0000313|EMBL:KOY87806.1, ECO:0000313|Proteomes:UP000037950}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=336/3 {ECO:0000313|EMBL:KOY87806.1,
RC   ECO:0000313|Proteomes:UP000037950};
RA   Isojarvi J., Battchikova N., Aro E.-M.;
RT   "Draft genome sequence of symbiotic bacteroides-like organism.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage of DNA to give random double-stranded
CC         fragments with terminal 5'-phosphates, ATP is simultaneously
CC         hydrolyzed.; EC=3.1.21.3; Evidence={ECO:0000256|ARBA:ARBA00000851};
CC   -!- SIMILARITY: Belongs to the HsdR family.
CC       {ECO:0000256|ARBA:ARBA00008598}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOY87806.1}.
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DR   EMBL; LJIE01000001; KOY87806.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M9DUW5; -.
DR   STRING; 1664068.AD998_18190; -.
DR   PATRIC; fig|1664068.3.peg.3702; -.
DR   OrthoDB; 9759819at2; -.
DR   Proteomes; UP000037950; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009035; F:type I site-specific deoxyribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR   CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR   Gene3D; 3.90.1570.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013670; EcoEI_R_C_dom.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR007409; Restrct_endonuc_type1_HsdR_N.
DR   PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR   PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR   Pfam; PF08463; EcoEI_R_C; 1.
DR   Pfam; PF04313; HSDR_N; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000313|EMBL:KOY87806.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037950};
KW   Restriction system {ECO:0000256|ARBA:ARBA00022747}.
FT   DOMAIN          175..370
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
SQ   SEQUENCE   937 AA;  108479 MW;  2D698CC5F4E84061 CRC64;
     MSTNKNQNPE QIARDKIDNM LTEAGWIIQS KNAIDLGAGK GVAIREYQVG TKFADYVLFV
     DKKPIGIIEA KKEEDGYQLT TAEDQSTEYA NAKLKYLNND PLPFIFESTG TITRFRDARD
     PKPRGRNIFW FFKPETLADW LKKDKTLRAR LQDIPVLNET GLRPAQIKAI NNLEISFKHA
     RPKALIQMAT GAGKTFTAAT FIYRLLEHAK AKRILFLVDT KNLGEQAEQE FMAFQPNESN
     RKFTELYNVQ RLTSSYIASD SQVCISTIQR MYAILKGEEL NEGAEEDNPN ESSWLKEQQE
     NKQALPIEYN PNVSIEQFDF IVVDECHRSI YNLWKQVLDY FDAFLIGLTA TPDKRTFGFF
     EENVVSEYTY EQSVIDGVNV PYEVYTIETE ISQKGSIVKA GWWIDKRDKF TRKTRWQQED
     EDTIYTKNDL DKNVVNQSQI RNIIREFKNA LQTTIFPNRK DEKGEYEVPK TLIFAKTDSH
     ADDIIKIVRD EFNESDEFCK KITYKIQEDP KSVLNRFRNA YYPRIAVTVD MIATGTDVKP
     LEVLLFMRDV KSINYFEQMK GRGTRTINKD SFQMVSKTAQ AKTHFVIVDA VGVTKSKKND
     SRPLERKPTV ALKDLLGAIT MGVTDEDLFL SLANRLIRLE KEITEKEKEK LLEFSKGKSL
     RQISKELLAA FDKDEIEEKA KAIIEAIPEQ NRTPEKIVEA QQQAQKELID EASSTFNGKL
     NDYIDHVRQT HEQIIDTYNI DTVTKSEWNT ASVDKAKEIV KDFSDYLLAN QDEIKALTIF
     YKQPYNRRNI TFKMIKEVFE KLKMDKPTLA PQYVWEAYKQ LENVKSTQPT DELTALVSLI
     RRACGIDKEL QAFDKTIDEN FKTWIFKQNA GKHNRFTPEQ MEWLREIKNH VVNSYHIEID
     DLDYTPFDEK GGKGKMYQLF GKEMNEIIDE LNGILVA
//