ID   A0A0M9UK26_9MICO        Unreviewed;       481 AA.
AC   A0A0M9UK26;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Cell division protein FtsI {ECO:0000313|EMBL:GAP77634.1};
DE            EC=2.4.1.129 {ECO:0000313|EMBL:GAP77634.1};
GN   ORFNames=Y09_0450 {ECO:0000313|EMBL:GAP77634.1};
OS   Brachybacterium sp. SW0106-09.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC   Brachybacterium.
OX   NCBI_TaxID=1704590 {ECO:0000313|EMBL:GAP77634.1, ECO:0000313|Proteomes:UP000037781};
RN   [1] {ECO:0000313|EMBL:GAP77634.1, ECO:0000313|Proteomes:UP000037781}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SW0106-09 {ECO:0000313|EMBL:GAP77634.1,
RC   ECO:0000313|Proteomes:UP000037781};
RA   Qin Q.L., Li Y., Zhang Y.Z.;
RT   "Genome Sequencing of Brachybacterium sp. SW0106-09.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAP77634.1}.
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DR   EMBL; BCAK01000003; GAP77634.1; -; Genomic_DNA.
DR   RefSeq; WP_053916040.1; NZ_BCAK01000003.1.
DR   AlphaFoldDB; A0A0M9UK26; -.
DR   Proteomes; UP000037781; Unassembled WGS sequence.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000313|EMBL:GAP77634.1};
KW   Cell division {ECO:0000313|EMBL:GAP77634.1};
KW   Glycosyltransferase {ECO:0000313|EMBL:GAP77634.1};
KW   Transferase {ECO:0000313|EMBL:GAP77634.1}.
FT   DOMAIN          155..476
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   481 AA;  50981 MW;  ADC4CB03F5BCC4B1 CRC64;
     MNKPLRHVWL VVGVLFVLLF TSTTYFQFVA QGRLAAHGQN QRTLQGEYGR HRGPIVVDGH
     AIATSQESGD TYGYLRTYDP GAMYAPITGY YSVVYGFTGI ERSLNDTLSG EADSLFYHRL
     ADVVSGRENQ GASVELTLDS AAQQAAWDAL DGRRGAVVAL DPETGAILAM VSAPSFDPNE
     LASHDTGAVS QAWSSLNEDP ERPLTNRAIG GDLYPPGSAF KLVTASAALE TGDYTADSVI
     PGPGTYELPN SSSVMNNFSE GRQEPCGPDD ESTLAEALRQ SCNTSFGMLG VEIGQDQLRS
     TAEEFGFGQD LSIPMGVTPS RIGEDLDDAQ LATTSIGQYE TRVTPLQMAM VGGAFANDGV
     VMQPQLVQAV RTGDLSTVSE LTPKEVGQPL SAANAAQMRQ MMVGVVEDGT GSAAAIDGVE
     VGGKTGTAEW GEDRSPHSWF VGYGQTDEQK IAVAVVVEEG GYGSRTAAPI ARDVMEAVIQ
     R
//