ID A0A0M9X7K2_9ACTN Unreviewed; 522 AA.
AC A0A0M9X7K2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Beta-N-acetylglucosaminidase {ECO:0000313|EMBL:KOT36610.1};
GN ORFNames=ADK41_22350 {ECO:0000313|EMBL:KOT36610.1};
OS Streptomyces caelestis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=36816 {ECO:0000313|EMBL:KOT36610.1, ECO:0000313|Proteomes:UP000037773};
RN [1] {ECO:0000313|EMBL:KOT36610.1, ECO:0000313|Proteomes:UP000037773}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-24567 {ECO:0000313|EMBL:KOT36610.1,
RC ECO:0000313|Proteomes:UP000037773};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOT36610.1}.
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DR EMBL; LGCN01000205; KOT36610.1; -; Genomic_DNA.
DR RefSeq; WP_037804601.1; NZ_LGCN01000205.1.
DR AlphaFoldDB; A0A0M9X7K2; -.
DR PATRIC; fig|36816.3.peg.4833; -.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000037773; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06564; GH20_DspB_LnbB-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR43678:SF1; BETA-N-ACETYLHEXOSAMINIDASE; 1.
DR PANTHER; PTHR43678; PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00640)-RELATED; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000037773}.
FT DOMAIN 54..171
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 178..480
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT REGION 25..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..75
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 321
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 522 AA; 56579 MW; E1571CD425A9831A CRC64;
MIGAVAAGAL VAASGVGLGL WAASGDDGGS AGPRAASPAK SPSPSRSYPL SKAPRTIPAV
REHTAERGPG WRPAKDHRVV VDDPALADEG RLTAAELGLA YAGEKGDRRA GDLRLELNRD
AGANPESYTM TVRDGRVTVT APGEAGVFYG TRTLKQEIEG AGAAPEGVVR DEPAKQRRGL
MLDTARKFYT ADWIEDRIRE LGDLKFNEIG LHFSDDQGFR VESDSHPEIV SAQHLTKAQV
KRIVDLAESR HITVVPEIDS PGHLGAVIAA HPDLQLRDAD GDAVRGAIDI SKPGAAEIVD
DLLDEYAGLF PGGQWHLGGD EYQALVVSDP EASFPELAAA ARERYGSGAT VEDLTTGWLN
DRAATVRGHD RTPRAWNDGF FRGGSVRAAK DIRVAYWTGK EIGARQPAEY LSEGREVINH
NDEFLYYVLG EPLTFVYPTG ERIYEQWTPR VLRGTTAVPE RYDDRILGGS FAVWGDIPRA
QTQDQVAAGI RLPLRATVQK LWDPDEPELS WARFRNLADE LG
//
