ID   A0A0M9XAF6_9ACTN        Unreviewed;       918 AA.
AC   A0A0M9XAF6;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:KOT43681.1};
GN   ORFNames=ADK41_05310 {ECO:0000313|EMBL:KOT43681.1};
OS   Streptomyces caelestis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=36816 {ECO:0000313|EMBL:KOT43681.1, ECO:0000313|Proteomes:UP000037773};
RN   [1] {ECO:0000313|EMBL:KOT43681.1, ECO:0000313|Proteomes:UP000037773}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-24567 {ECO:0000313|EMBL:KOT43681.1,
RC   ECO:0000313|Proteomes:UP000037773};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOT43681.1}.
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DR   EMBL; LGCN01000051; KOT43681.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M9XAF6; -.
DR   PATRIC; fig|36816.3.peg.1131; -.
DR   Proteomes; UP000037773; Unassembled WGS sequence.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00009; AAA; 1.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037773}.
FT   DOMAIN          851..916
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
FT   COILED          759..786
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   918 AA;  97540 MW;  6D2BFD1C2215F910 CRC64;
     MVIGREELYS EAREQLARGG SVLLHGPAGI GKSTVLRALA AENAGATGTV LRCSATESES
     HLPFLALADL FGLVLDRVSA RLPAAQRTAL ESALTGRGES TLQRDGLALR LAVLSTLRAL
     AAEGPVLVVA DDLQWLDSAS AELLGFAARR LGDSPVRMLC AVRTDGEEYD RQLRACPPDT
     LAVRLGPFSR TQVSALLDHR GYTGLSRSTT RDIHRTSGGN PLFALELGRA LAESPARPRP
     GEPLPVPTSL RALVLSRLEM LSDEARRTLL VASAGARPTL ALLHAAGREN AEAETAQAVA
     LGLLATDPEE PALRFAHPLI SAALYAEAPA GERRAVHTAL STAASDPIER ARHLALAATG
     PDPEVAARLA GAAALARDRG APSVAASLGL LAARHTPADG EPGPDARRLR AAEDAITAGE
     ADLARDIARE VLTRATAPAE RVRAWMVVIE AAGQALGEVD AVFPQVLADA GDDPRLLALV
     HYQLAWREVV VDGDFAKSRQ EAAHAAELAA RGGDRRTELL ALAFQSSTET LMGHPDAPAT
     IQRALQEPQD PDVACHHNGA AMARFRWLLM SDRLPEARTA ITALLREARR RGMVESEVHF
     SRLLADTELR FGHCGRALDL ARESLRMARD SGIGESASAM LASLAEASGG DVDRALTLAR
     EAADHAEVDG DQLYLSLALA ALGYAQSVAG DAQAAVRSLR RVRELEHGMG ISDPARGRWQ
     GDLAEALVRI GEVGEAQELI DVTRTHALRL NRASVLAVLD RAEALVRAAR GEHQAAHAQL
     ASAQERLGKL GYGLEEARSA FALARLRGRA PGAYDEAARL FRRCRALPWL RQVERAVTAG
     PTEPETVPAA APSALDGLAA MERQVAALVM EGATNREIAG RLFISVKTVE ATLTRVYRKL
     GIRSRVDIVR LAAGRRTP
//