ID A0A0M9YB25_9ACTN Unreviewed; 756 AA.
AC A0A0M9YB25;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Molybdopterin oxidoreductase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ADK55_34940 {ECO:0000313|EMBL:KOU38300.1};
OS Streptomyces sp. WM4235.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415551 {ECO:0000313|EMBL:KOU38300.1, ECO:0000313|Proteomes:UP000037699};
RN [1] {ECO:0000313|EMBL:KOU38300.1, ECO:0000313|Proteomes:UP000037699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM4235 {ECO:0000313|EMBL:KOU38300.1,
RC ECO:0000313|Proteomes:UP000037699};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU38300.1}.
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DR EMBL; LGDE01000470; KOU38300.1; -; Genomic_DNA.
DR RefSeq; WP_053684907.1; NZ_LGDE01000470.1.
DR AlphaFoldDB; A0A0M9YB25; -.
DR PATRIC; fig|1415551.3.peg.7619; -.
DR OrthoDB; 5287431at2; -.
DR Proteomes; UP000037699; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR CDD; cd02787; MopB_CT_ydeP; 1.
DR CDD; cd02767; MopB_ydeP; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037951; MopB_CT_YdeP.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR InterPro; IPR041953; YdeP_MopB.
DR NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR PIRSF; PIRSF000144; CbbBc; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000037699}.
FT DOMAIN 120..489
FT /note="Molybdopterin oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00384"
FT DOMAIN 642..749
FT /note="Molybdopterin dinucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF01568"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 756 AA; 81999 MW; 233792749E7F24C9 CRC64;
MATKPPAGDP VQDSPRIAPP GRAAAGLPAI GHTLRIAQQQ MGLARTARTL LKVNQKDGFD
CPGCAWPEGD KRHTAEFCEN GAKAVAEEAT LRRVTPEFFA AHPLADLEGR SGYWLGQQGR
ITEPMLLPEG GDRYEPVSWE RAFAIIAEEL TALGSPDEAL FYTSGRTSNE AAFLFQLFAR
EFGTNNLPDC SNMCHESSGS ALNETIGIGK GSVSLEDLHQ AELIIVAGQN PGTNHPRMLS
ALERAKSAGA KIISVNPLPE AGMERFKNPQ TPLGMLRGTA LNDLFLQIRI GGDQALFRLL
NKLVIETDGA TDEEFIREHT HGYEDLAAAA AKTDWDETLT ATGLTRPEIE SALAMVLASK
RTIVCWAMGL TQHKHSVATI REVVNLLLLR GDIGRPGAGV CPVRGHSNVQ GDRTMGIFER
PAPAFLDALD REFGITSPRR HGFDVVRSIE ALRDGEAKVL FAMGGNFVGA TPDTAVTEAA
IRRASLTVHV STKLNRSHAV TGRRALILPT LGRTDKDVQA AGRQFVTVED SMGMVHASRG
NLAPASPHLL SEPAIVARLA RAVLGAASAT PWEEFERDYG TIRDRISRVV PGFEDFNARA
ARPEGFRLPH APRDERRFPT KTGKANFTAA PVEYPRVPEG RLLLQTLRSH DQYNTTIYGL
DDRYRGITGG RRVVMVNPLD AAELGLVDGA YTDIVGEWRD GVERRAPGFR IVHYPTARGC
AAAYYPETNV LVPLDSTADT SNTPASKSVV VRFEPA
//
