ID A0A0M9YBJ8_9ACTN Unreviewed; 416 AA.
AC A0A0M9YBJ8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=3'-5' exonuclease {ECO:0000313|EMBL:KOU38613.1};
GN ORFNames=ADK55_34555 {ECO:0000313|EMBL:KOU38613.1};
OS Streptomyces sp. WM4235.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415551 {ECO:0000313|EMBL:KOU38613.1, ECO:0000313|Proteomes:UP000037699};
RN [1] {ECO:0000313|EMBL:KOU38613.1, ECO:0000313|Proteomes:UP000037699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM4235 {ECO:0000313|EMBL:KOU38613.1,
RC ECO:0000313|Proteomes:UP000037699};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU38613.1}.
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DR EMBL; LGDE01000469; KOU38613.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M9YBJ8; -.
DR PATRIC; fig|1415551.3.peg.7534; -.
DR Proteomes; UP000037699; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd06142; RNaseD_exo; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR041605; Exo_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR47649; RIBONUCLEASE D; 1.
DR PANTHER; PTHR47649:SF1; RIBONUCLEASE D; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF18305; DNA_pol_A_exoN; 1.
DR Pfam; PF00570; HRDC; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00341; HRDC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|EMBL:KOU38613.1};
KW Hydrolase {ECO:0000313|EMBL:KOU38613.1};
KW Nuclease {ECO:0000313|EMBL:KOU38613.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037699}.
FT DOMAIN 236..316
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 314..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 416 AA; 44673 MW; 48696E9E434CB494 CRC64;
MRTTTGGGPP DEEVSSDGLP VPLLEPREGI PPVVADAESL AEVVAAFAAG TGPVAVDAER
ASGYRYGQRA YLVQLRREGA GSALIDPVGC PDLSSLGEAL SGTEWILHAA TQDLPCLREI
GMAPTSLFDT ELAGRLAGFP RVGLGAMVES VLGYTLEKGH SAVDWSTRPL PEPWLRYAAL
DVELLVDLRD ALEKELDRQG KLDWAHQEFD AIASAPPAPP RKDPWRRTSG MHKVRRRRQM
AVVRELWESR DRIAQRRDVS PGKVLGDAAI VEAALAMPLN ASALSALPGY GQRMGRRQLE
QWMAAVDRAK ALSENELPQP GATPAGPPPP RSWADKDPAA AARLSAARAA VTALAEGLNL
PQENLITPDT VRRLCWEPPQ RLEADTVSEA LAAHGARTWQ IEQVTPALVE ALAATD
//
