ID A0A0M9YFA7_9ACTN Unreviewed; 359 AA.
AC A0A0M9YFA7;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KOU45136.1};
GN ORFNames=ADK54_15305 {ECO:0000313|EMBL:KOU45136.1};
OS Streptomyces sp. WM6378.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415557 {ECO:0000313|EMBL:KOU45136.1, ECO:0000313|Proteomes:UP000037774};
RN [1] {ECO:0000313|Proteomes:UP000037774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6378 {ECO:0000313|Proteomes:UP000037774};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU45136.1}.
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DR EMBL; LGDD01000166; KOU45136.1; -; Genomic_DNA.
DR RefSeq; WP_053726179.1; NZ_LGDD01000166.1.
DR AlphaFoldDB; A0A0M9YFA7; -.
DR PATRIC; fig|1415557.3.peg.3416; -.
DR OrthoDB; 1938857at2; -.
DR Proteomes; UP000037774; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..68
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 337..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 359 AA; 38383 MW; DD6A5C398945B990 CRC64;
MSEIESDAPP PRRPTMKDVA REAGVSTSAV SFALNNRPGV SDSTRRRVIR VADRLGWRPS
SAARALSGEN AGAIGLVLAR PADSLGGESF FLQLVSGIQA SLAPRDQALV FQMVDDVQAE
CELYRRWWAQ RRVDGVIVVD PRVSDPRPET LAVLGLPAVV IGGMEAPGNP GAPRLPRQAR
LSNIWADDSG AMDLIVRHLY ALGHRRIGHI AGTPGFAHTA RRIASLRAAG RRLGLEQAVS
VTTDFTDRQG AKAARRLFSS PAAPTALICD NEVMAVAAVS VAAERGLLIP RDVSVVSWED
SVICHTLHPL LTALVRKADE FGHRAAGELL ALLDGGPARQ VQDPLPRLQP RESTAPPPA
//
