ID A0A0M9YWE8_9ACTN Unreviewed; 231 AA.
AC A0A0M9YWE8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=ADK57_13670 {ECO:0000313|EMBL:KOU69267.1};
OS Streptomyces sp. MMG1533.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415546 {ECO:0000313|EMBL:KOU69267.1, ECO:0000313|Proteomes:UP000037741};
RN [1] {ECO:0000313|Proteomes:UP000037741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1533 {ECO:0000313|Proteomes:UP000037741};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU69267.1}.
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DR EMBL; LGDG01000122; KOU69267.1; -; Genomic_DNA.
DR RefSeq; WP_053749694.1; NZ_LGDG01000122.1.
DR AlphaFoldDB; A0A0M9YWE8; -.
DR STRING; 1415546.ADK57_13670; -.
DR PATRIC; fig|1415546.3.peg.2983; -.
DR OrthoDB; 9792284at2; -.
DR Proteomes; UP000037741; Unassembled WGS sequence.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037741};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 28..228
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 231 AA; 23929 MW; 60CB28F568B21EE8 CRC64;
MAKILFVMTG ADRWTLADGS THPTGFWAEE AVAPYEAFKA AGHEVTVATP GGVVPPVDQG
SLGSGANGGP EQAAKIRAVV ETAPELRAPI ALTDVRLDEY DAVYVPGGHG PMEDLAVNAD
SGTILTRAVG SGMPVGVVCH GPAALLAAVK EDGTNAYAGF RITAFTNTEE QLAGNAERAK
WLLQDRLTEA GLKVEVGEPW APHVEVDRNV VTGQNPASSA PLAAELLKKL A
//
