ID A0A0M9YXD6_9ACTN Unreviewed; 401 AA.
AC A0A0M9YXD6;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Diaminopimelate decarboxylase {ECO:0000313|EMBL:KOU75906.1};
GN ORFNames=ADK57_05765 {ECO:0000313|EMBL:KOU75906.1};
OS Streptomyces sp. MMG1533.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415546 {ECO:0000313|EMBL:KOU75906.1, ECO:0000313|Proteomes:UP000037741};
RN [1] {ECO:0000313|Proteomes:UP000037741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1533 {ECO:0000313|Proteomes:UP000037741};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR600183-50};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-II family.
CC {ECO:0000256|RuleBase:RU003737}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU75906.1}.
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DR EMBL; LGDG01000028; KOU75906.1; -; Genomic_DNA.
DR RefSeq; WP_053748247.1; NZ_LGDG01000028.1.
DR AlphaFoldDB; A0A0M9YXD6; -.
DR STRING; 1415546.ADK57_05765; -.
DR PATRIC; fig|1415546.3.peg.1270; -.
DR OrthoDB; 9802241at2; -.
DR Proteomes; UP000037741; Unassembled WGS sequence.
DR GO; GO:0016830; F:carbon-carbon lyase activity; IEA:UniProt.
DR CDD; cd06843; PLPDE_III_PvsE_like; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR022643; De-COase2_C.
DR InterPro; IPR022657; De-COase2_CS.
DR InterPro; IPR022644; De-COase2_N.
DR InterPro; IPR000183; Orn/DAP/Arg_de-COase.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR43727; DIAMINOPIMELATE DECARBOXYLASE; 1.
DR PANTHER; PTHR43727:SF2; DIAMINOPIMELATE DECARBOXYLASE 1, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF02784; Orn_Arg_deC_N; 1.
DR Pfam; PF00278; Orn_DAP_Arg_deC; 1.
DR PRINTS; PR01179; ODADCRBXLASE.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
DR PROSITE; PS00879; ODR_DC_2_2; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR600183-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000037741}.
FT DOMAIN 28..275
FT /note="Orn/DAP/Arg decarboxylase 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02784"
FT DOMAIN 276..373
FT /note="Orn/DAP/Arg decarboxylase 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00278"
FT ACT_SITE 346
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
FT MOD_RES 52
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
SQ SEQUENCE 401 AA; 43155 MW; 8EB52F783C770998 CRC64;
MTDPTPAVRD RILALPSTEL PAYVYDLAAL RTHATAVRDA LPERVELYYA AKANPEPEIL
AALGPYVDGY EVSSGGELAH VAKAVPGRPL AFGGPGKTPD EVTAALEHGV ERFHVESEYE
LRMLAELARR IAPRRRVAVL PRVNLPVTDG SLAGSALAMG GRPTPFGMDP VRAEAVVHAL
ADGTYPHLEL RGIHAHLASG LQAAEQLSVA ETVVSWVTAL GVPPAEVNVG GGMTVDYTHP
ERRFDWAAYG NGLARLTEAH PELTLRIEPG RALTAYCGWY ATEVLDVKRS HGEEFAVVRG
GTHHLRTPAT KGHDQPCSVL PVDTWPHPWP RPAAEGERIT VAGQLCTPKD VLARQVPAPG
LRAGDRVVFS LAGAYAWNIS HHAFLMHPEP GFHFLDTASA R
//
