ID A0A0M9ZXR0_9ACTN Unreviewed; 588 AA.
AC A0A0M9ZXR0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:KOV79438.1};
GN ORFNames=ADL01_13075 {ECO:0000313|EMBL:KOV79438.1};
OS Streptomyces sp. NRRL WC-3618.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519490 {ECO:0000313|EMBL:KOV79438.1, ECO:0000313|Proteomes:UP000037738};
RN [1] {ECO:0000313|EMBL:KOV79438.1, ECO:0000313|Proteomes:UP000037738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL WC-3618 {ECO:0000313|EMBL:KOV79438.1,
RC ECO:0000313|Proteomes:UP000037738};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV79438.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LGDW01000107; KOV79438.1; -; Genomic_DNA.
DR RefSeq; WP_053742125.1; NZ_LGDW01000107.1.
DR AlphaFoldDB; A0A0M9ZXR0; -.
DR PATRIC; fig|1519490.3.peg.2869; -.
DR OrthoDB; 9813184at2; -.
DR Proteomes; UP000037738; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000037738}.
FT DOMAIN 13..325
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 371..481
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 502..560
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 160
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 236
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 588 AA; 63465 MW; C1AD85C8448B3639 CRC64;
MPAPALTTTS DGFLLHGEPF RIISGAMHYF RVHPDQWADR LRKARLMGLN TVETYVPWNL
HQPEPGTLVL DGILDLPRYL RLAKAEGLHV LLRPGPFICA EWDGGGLPSW LTTDPDIRLR
SSDPRFTGAI DRYLDLLLPP LLPYLAESGG PVIAVQVENE YGAYGDDAAY LEHLAEALRS
RGIGELLFTC DQANPEHLAA GSLPGVLTTG TFGSKVAASL EQLRAHQPEG PLVCAEFWIG
WFDHWGEEHH TRDAADAAAD LDRLLSAGAS VNIYMFHGGT NFAFTNGANH DHAYQPMVTS
YDYDAALTES GDPGPKYHAF REVIARHAPV PDEPVPAPSV KLPSTVVELG QSASLLPHAG
LLAKPVRTED PATMDELGLR AGYVLYRTTA PLAGDGLLHF AGGVGDRAQV FVDGAPVGVL
ERERHDESLP VRIPFAGASV EVLVENMGGV NYGPRIGSPK GLLGAVTFNG TALRGWDSHP
LTLNDLSALP LAPHDGSPAT QPTFYQGTFE VQAPADTFLS LPGWTKGQAW INGFHLGRYW
NRGPQRTLYV PAPVLRPGAN ELLLLELNAT TSAQVLLTDT PDLGPVKP
//
