ID A0A0N0CXG5_9BACT Unreviewed; 378 AA.
AC A0A0N0CXG5;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Cysteine desulfurase IscS {ECO:0000313|EMBL:KOY84524.1};
DE EC=2.8.1.7 {ECO:0000313|EMBL:KOY84524.1};
GN ORFNames=AD998_20225 {ECO:0000313|EMBL:KOY84524.1};
OS bacterium 336/3.
OC Bacteria.
OX NCBI_TaxID=1664068 {ECO:0000313|EMBL:KOY84524.1, ECO:0000313|Proteomes:UP000037950};
RN [1] {ECO:0000313|EMBL:KOY84524.1, ECO:0000313|Proteomes:UP000037950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=336/3 {ECO:0000313|EMBL:KOY84524.1,
RC ECO:0000313|Proteomes:UP000037950};
RA Isojarvi J., Battchikova N., Aro E.-M.;
RT "Draft genome sequence of symbiotic bacteroides-like organism.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU004504};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. NifS/IscS subfamily.
CC {ECO:0000256|ARBA:ARBA00006490}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOY84524.1}.
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DR EMBL; LJIE01000003; KOY84524.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N0CXG5; -.
DR STRING; 1664068.AD998_20225; -.
DR PATRIC; fig|1664068.3.peg.4129; -.
DR OrthoDB; 9808002at2; -.
DR Proteomes; UP000037950; Unassembled WGS sequence.
DR GO; GO:0031071; F:cysteine desulfurase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR020578; Aminotrans_V_PyrdxlP_BS.
DR InterPro; IPR016454; Cysteine_dSase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11601:SF34; CYSTEINE DESULFURASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11601; CYSTEINE DESULFURYLASE FAMILY MEMBER; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR PIRSF; PIRSF005572; NifS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00595; AA_TRANSFER_CLASS_5; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000037950};
KW Transferase {ECO:0000313|EMBL:KOY84524.1}.
FT DOMAIN 7..369
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 378 AA; 41583 MW; DF4AF827D360F4BC CRC64;
MNIKQITYLD YNSTTPIDQR VFKAILPYLQ GNFANPSSTH YFGQSINEGV KQARNAIANF
INAESNELIF TSGATEAINL AIKGVVESYS EKGKHIITAS TEHKAVLDTC KDLERKGFEV
SYLSVQNNGL MDLNELKQTI RTDTILVSVM YVNNETGIIQ PIKEISKIAQ EKGVLFMTDA
TQAVGKIEID VDDLGVDLMC FSGHKIYAPK GIGALFVRQR GNKVKLIPLI HGGGHEQGLR
SGTLNVPGIM ALAKACEIAS QEMIKNEKTI RELRNTLEIE LLKLPNTSLN GDSRSRLYNV
CNICFRGQDA NVLIGRMKDI AVSNGSACTS AVEEPSHVLK AMGISNEDAF ASIRFSLGKY
NTLSEIEYVI SKLKILMQ
//
