ID   A0A0N0M1C7_9SPHN        Unreviewed;       464 AA.
AC   A0A0N0M1C7;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Cytosol aminopeptidase {ECO:0000313|EMBL:KPH64489.1};
DE   SubName: Full=Leucyl aminopeptidase {ECO:0000313|EMBL:TCM31136.1};
GN   ORFNames=ADT71_11515 {ECO:0000313|EMBL:KPH64489.1}, EDF59_12570
GN   {ECO:0000313|EMBL:TCM31136.1};
OS   Novosphingobium sp. ST904.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Novosphingobium.
OX   NCBI_TaxID=1684385 {ECO:0000313|EMBL:KPH64489.1, ECO:0000313|Proteomes:UP000037878};
RN   [1] {ECO:0000313|EMBL:KPH64489.1, ECO:0000313|Proteomes:UP000037878}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ST904 {ECO:0000313|EMBL:KPH64489.1,
RC   ECO:0000313|Proteomes:UP000037878};
RA   Thijs S., Bottos E.M., Van Hamme J.D., Gkorezis P., Rineau F.,
RA   Vangronsveld J.;
RT   "Novosphingobium nitrophenolicus strain ST904 degrades p-nitrophenol and
RT   stimulates plant growth.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:TCM31136.1, ECO:0000313|Proteomes:UP000295740}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ST904 {ECO:0000313|EMBL:TCM31136.1,
RC   ECO:0000313|Proteomes:UP000295740};
RA   Whitman W.;
RT   "Genomic Encyclopedia of Type Strains, Phase IV (KMG-V): Genome sequencing
RT   to study the core and pangenomes of soil and plant-associated
RT   prokaryotes.";
RL   Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M17 family.
CC       {ECO:0000256|ARBA:ARBA00009528}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPH64489.1}.
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DR   EMBL; LGJH01000140; KPH64489.1; -; Genomic_DNA.
DR   EMBL; SLVC01000025; TCM31136.1; -; Genomic_DNA.
DR   RefSeq; WP_054437025.1; NZ_SLVC01000025.1.
DR   AlphaFoldDB; A0A0N0M1C7; -.
DR   STRING; 1684385.ADT71_11515; -.
DR   PATRIC; fig|1684385.3.peg.3119; -.
DR   OrthoDB; 9809354at2; -.
DR   Proteomes; UP000037878; Unassembled WGS sequence.
DR   Proteomes; UP000295740; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00433; Peptidase_M17; 1.
DR   Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR011356; Leucine_aapep/pepB.
DR   InterPro; IPR043472; Macro_dom-like.
DR   InterPro; IPR000819; Peptidase_M17_C.
DR   InterPro; IPR048816; Peptidase_M17_N_1.
DR   PANTHER; PTHR11963:SF53; AMINOPEPTIDASE; 1.
DR   PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR   Pfam; PF00883; Peptidase_M17; 1.
DR   Pfam; PF21337; Peptidase_M17_N_1; 1.
DR   PRINTS; PR00481; LAMNOPPTDASE.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR   PROSITE; PS00631; CYTOSOL_AP; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW   ECO:0000313|EMBL:KPH64489.1}; Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037878}.
FT   DOMAIN          308..315
FT                   /note="Cytosol aminopeptidase"
FT                   /evidence="ECO:0000259|PROSITE:PS00631"
SQ   SEQUENCE   464 AA;  49328 MW;  42F3F30EBD177C41 CRC64;
     MTDKNALIQP DRGQKAVALH LIGKDGLEQF IKGLSVPQRA ALEAQKFAGA AGSHAILPDG
     DGWFVAAGVA DPAKLSTWCL ARLAEVLPAG TYRRASGEPG KAALGWIAGQ YSFDRYLSDP
     SEEGPRILLT GEVKAIDAVI AEAEAIELVR DLVNTPAEDM GPGQLESEAE SLAKAFRAEV
     KITRGEMLER EYPMVHAVGR AAGRAHAPRL IELEWGDPKH PRIAVVGKGV CFDSGGLDIK
     PGAGMLLMKK DMGGAAHALA LARLIMGARL PVRLHLVIPA VENAISGNSF RPGDVLRSRA
     GITVEIGNTD AEGRLILGDA LTRASEKEPE LVIDFATLTG AARVAVGPDL PALFAREDAT
     AQAILDAGIG VDDPCWRLPL YDGYRDYLKS DIADINNAGS SGFAGASTAA LFMDRFVAKG
     LDWAHFDTFA WRPASKPGRP KGGDALGLRA AWYMLQQRYT GERG
//