ID A0A0N0MSD2_9ACTN Unreviewed; 380 AA.
AC A0A0N0MSD2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Beta-ketoacyl-acyl-carrier-protein synthase I {ECO:0000313|EMBL:KPI05408.1};
DE EC=2.3.1.41 {ECO:0000313|EMBL:KPI05408.1};
GN ORFNames=OK006_0695 {ECO:0000313|EMBL:KPI05408.1};
OS Actinobacteria bacterium OK006.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1592326 {ECO:0000313|EMBL:KPI05408.1, ECO:0000313|Proteomes:UP000037912};
RN [1] {ECO:0000313|EMBL:KPI05408.1, ECO:0000313|Proteomes:UP000037912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OK006 {ECO:0000313|EMBL:KPI05408.1,
RC ECO:0000313|Proteomes:UP000037912};
RA Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT "Draft genome sequences for four Actinobacteria strains OK006 OK074 OV450
RT and OV320.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI05408.1}.
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DR EMBL; LJCU01000236; KPI05408.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N0MSD2; -.
DR PATRIC; fig|1592326.3.peg.7382; -.
DR Proteomes; UP000037912; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF320; BETA-KETOACYL SYNTHASE; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:KPI05408.1};
KW Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:KPI05408.1}.
FT DOMAIN 1..378
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 380 AA; 39415 MW; DEC55AB6A8B565DC CRC64;
MSEHPGWPIA GAGAVAAIGR SPAEIFDALC AGTSGLHPMR GFDRSHYTGD RLFEIDDRVG
SGDVPGRASA FLLDAIGQAL AAAGMGEQLG DTPVLVGTGL RELRSVELWA REGIPWSADR
LHFGHALRER FGATVTYTFS NACSASLYAL SMACDLLAGG AETVVVAGVD VVTESMVGVA
DRLQSVAPDT VRPFDRNRRG TILGEGASAV VLRRTREPGR PYLGRVRGVA VNCDAHHATA
PHAGNIAAAV HDAHRRAGTG PKDVDLVMLH GTGTHANDVA EAQAMRAVFG TTPEKTLMTA
MKSMTGHTSG ASGLHSLIIA LRAMADGLVP PTLGLDEPID EVADFRIVRG APAPADLALA
QVNAFGFGGI NAVALVAGDR
//
