ID   A0A0N0N888_9ACTN        Unreviewed;       231 AA.
AC   A0A0N0N888;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE            EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN   ORFNames=OV320_0874 {ECO:0000313|EMBL:KPI23359.1};
OS   Actinobacteria bacterium OV320.
OC   Bacteria; Actinomycetota; Actinomycetes.
OX   NCBI_TaxID=1592329 {ECO:0000313|EMBL:KPI23359.1, ECO:0000313|Proteomes:UP000037870};
RN   [1] {ECO:0000313|EMBL:KPI23359.1, ECO:0000313|Proteomes:UP000037870}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OV320 {ECO:0000313|EMBL:KPI23359.1,
RC   ECO:0000313|Proteomes:UP000037870};
RA   Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT   "Draft genome sequences for four actinobacteria strains OK006 OK074 OV450
RT   and OV320.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC         Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC         Evidence={ECO:0000256|ARBA:ARBA00001524};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPI23359.1}.
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DR   EMBL; LJCX01000033; KPI23359.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N0N888; -.
DR   PATRIC; fig|1592329.3.peg.8674; -.
DR   Proteomes; UP000037870; Unassembled WGS sequence.
DR   CDD; cd03141; GATase1_Hsp31_like; 1.
DR   Gene3D; 3.40.50.880; -; 1.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   InterPro; IPR002818; DJ-1/PfpI.
DR   PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR   PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR   Pfam; PF01965; DJ-1_PfpI; 1.
DR   SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000037870};
KW   Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT   DOMAIN          28..229
FT                   /note="DJ-1/PfpI"
FT                   /evidence="ECO:0000259|Pfam:PF01965"
SQ   SEQUENCE   231 AA;  24821 MW;  01CA9748AE4D1A77 CRC64;
     MAKILFVITA SDHWTLADGT RQPAGFWAEE AIGPYQVFKE AGFEIAAATP GGVPPTADAL
     SLTADFNGGE QGAQRMRTAL HEATELAHPM RIEDVDIHDY VAVFYPGGWG PMEDLPDDAA
     SGKLLTEWLA SGKPVSLVCH GPAALLATVR PDGTSPFAGY RLTGLSNAEE KQNGLADRAK
     WLLQDRLVDE LAADYRETEP FAPHVEVDRT LFTGQNPGSA VPLARELLKA L
//