ID A0A0N0SKM8_9ACTN Unreviewed; 316 AA.
AC A0A0N0SKM8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE AltName: Full=UDP-glucose pyrophosphorylase {ECO:0000256|RuleBase:RU361259};
GN ORFNames=ADK57_25485 {ECO:0000313|EMBL:KOU62006.1};
OS Streptomyces sp. MMG1533.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415546 {ECO:0000313|EMBL:KOU62006.1, ECO:0000313|Proteomes:UP000037741};
RN [1] {ECO:0000313|Proteomes:UP000037741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1533 {ECO:0000313|Proteomes:UP000037741};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872,
CC ECO:0000256|RuleBase:RU361259};
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890, ECO:0000256|RuleBase:RU361259}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU62006.1}.
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DR EMBL; LGDG01000223; KOU62006.1; -; Genomic_DNA.
DR RefSeq; WP_053751886.1; NZ_LGDG01000223.1.
DR AlphaFoldDB; A0A0N0SKM8; -.
DR STRING; 1415546.ADK57_25485; -.
DR PATRIC; fig|1415546.3.peg.5531; -.
DR OrthoDB; 9803306at2; -.
DR Proteomes; UP000037741; Unassembled WGS sequence.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR CDD; cd02541; UGPase_prokaryotic; 1.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR01099; galU; 1.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU361259,
KW ECO:0000313|EMBL:KOU62006.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037741};
KW Transferase {ECO:0000256|RuleBase:RU361259, ECO:0000313|EMBL:KOU62006.1}.
FT DOMAIN 18..276
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 316 AA; 34083 MW; 622651CF8F09F3F7 CRC64;
MIVPHTTATP APARPVRKAV VPAAGLGTRF LPATKATPKE MLPVVDKPAI QYVVEEAAAA
GLDDVLMVTG RHKRAIEDHF DNAFELEQAL AAKGDAVRLD AVRDPARLAS IHHIRQGEPL
GLGHAVLCAR RHVGDQPFAV LLGDDLIDPR ETLLSRMLDV RDQYAGSVVA LMEVPREQIH
LYGCAAVEPT GERDVVRVTG LVEKPSPQDA PSAYAVIGRY VLDPAVFDTL ERTPPGRGGE
IQLTDALQDL ASGGTVHGVV FDGLRYDTGD KADYLRTVVR LACDRPDLGP EFTAWLKEFV
AGLEGAEATE RERFAA
//
