ID A0A0N0T5J3_9NOCA Unreviewed; 448 AA.
AC A0A0N0T5J3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=GntR family transcriptional regulator {ECO:0000313|EMBL:KOV76728.1};
GN ORFNames=ADL03_43480 {ECO:0000313|EMBL:KOV76728.1};
OS Nocardia sp. NRRL S-836.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1519492 {ECO:0000313|EMBL:KOV76728.1, ECO:0000313|Proteomes:UP000037746};
RN [1] {ECO:0000313|Proteomes:UP000037746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-836 {ECO:0000313|Proteomes:UP000037746};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV76728.1}.
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DR EMBL; LGDY01000165; KOV76728.1; -; Genomic_DNA.
DR RefSeq; WP_053739474.1; NZ_LGDY01000165.1.
DR AlphaFoldDB; A0A0N0T5J3; -.
DR STRING; 1519492.ADL03_43480; -.
DR PATRIC; fig|1519492.3.peg.9298; -.
DR OrthoDB; 199743at2; -.
DR Proteomes; UP000037746; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000037746};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 16..84
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 448 AA; 49025 MW; F2BEEBB4345B777C CRC64;
MSANWSTFRE LLLPEHQRRR GVEAALRRAI RDGRLTPGTR LPSSRDLAAQ LDVARGTVTS
AYTQLVAEGY LTARRGSGTT VAALGPAGTC GVPEPPRRWR YNLRPGLPAL SAFPRADWVA
AHRAALAELP DDDLAYPDPA GFLGLRKEIV DYLARVRAVV ARDAVITNGA ADGLQLTARL
LNGSIAVEEP SHFGGADMLR SHGLTPVPIP VDDKGIRVDL LARTDCRAVL VTAAHQFPLG
VVLHPERRRA LVEWARSRDG LIIEDDYDAE HRYDRPALGA LQALAPDHVV YQGTTSKVLA
PALRLGWLVV PERLRAGIVD RKKYNDMGTG TIPQAAFAHL LRTGGYDRHL RRTRALYRKR
RDALLEAVST HLPSWQPIGV AAGLHVVLRM PDGSDDMALK HALEARGVHV WALAQYARTP
MWPGLVLGYA ALTPDRLREA VREIAAVV
//
