ID   A0A0N1B1U7_9PROT        Unreviewed;       330 AA.
AC   A0A0N1B1U7;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:KPF66701.1};
GN   ORFNames=IP84_15655 {ECO:0000313|EMBL:KPF66701.1};
OS   beta proteobacterium AAP99.
OC   Bacteria; Pseudomonadota; Betaproteobacteria.
OX   NCBI_TaxID=1523428 {ECO:0000313|EMBL:KPF66701.1, ECO:0000313|Proteomes:UP000037960};
RN   [1] {ECO:0000313|EMBL:KPF66701.1, ECO:0000313|Proteomes:UP000037960}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AAP99 {ECO:0000313|EMBL:KPF66701.1,
RC   ECO:0000313|Proteomes:UP000037960};
RA   Zeng Y., Feng F., Liu Y., Koblizek M.;
RT   "Novel Diversity of Limnic Aerobic Anoxygenic Phototrophic Bacteria as
RT   Revealed by High-throughput Strain Identification and Genome Sequencing.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPF66701.1}.
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DR   EMBL; LJIA01000020; KPF66701.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N1B1U7; -.
DR   STRING; 1523428.IP84_15655; -.
DR   PATRIC; fig|1523428.3.peg.2012; -.
DR   Proteomes; UP000037960; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037960}.
FT   DOMAIN          226..320
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
SQ   SEQUENCE   330 AA;  36793 MW;  E79F209E3E191BBC CRC64;
     MIPVTILTGF LGAGKTTLLN RILTERHGEK IAVIENEFGQ EGIDNEILVQ EANEQIVEMN
     NGCICCTVRG DLVKILNDLH TKKKTGALQF DRVLIETTGM ADPGPVTQTF FMDDDVADRY
     LLDAVITVVD AKHGWNTLDA QKEAQSQVGF ADRILMSKVD VAEAEQVTAL KQRIKQMNPR
     APITEVHFGQ ADIKELLDIR GFNLNSILEI DPEFLTSDKH AHDGSVHSFV FTSDKPLDGV
     RLEEFLSAIL QVYGNDLLRY KGVLWLDGVE RRMVFQGVHM MMGADAGKPW QPGEKRSSKM
     VFIGRKMPVQ VIMDGLRQCE IGAGKTLKKK
//