ID A0A0N1G9C5_9ACTN Unreviewed; 1101 AA.
AC A0A0N1G9C5;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Non-ribosomal peptide synthetase domain protein {ECO:0000313|EMBL:KPI17813.1};
DE EC=5.1.1.11 {ECO:0000313|EMBL:KPI17813.1};
GN ORFNames=OK074_8092 {ECO:0000313|EMBL:KPI17813.1};
OS Actinobacteria bacterium OK074.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1592327 {ECO:0000313|EMBL:KPI17813.1, ECO:0000313|Proteomes:UP000037991};
RN [1] {ECO:0000313|EMBL:KPI17813.1, ECO:0000313|Proteomes:UP000037991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OK074 {ECO:0000313|EMBL:KPI17813.1,
RC ECO:0000313|Proteomes:UP000037991};
RA Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT "Draft genome sequences for four actinobacteria strains OK006 OK074 OV450
RT and OV320.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI17813.1}.
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DR EMBL; LJCV01000074; KPI17813.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N1G9C5; -.
DR PATRIC; fig|1592327.3.peg.2503; -.
DR Proteomes; UP000037991; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0047462; F:phenylalanine racemase (ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR018357; Hexapep_transf_CS.
DR InterPro; IPR012728; NRPS_C.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR NCBIfam; TIGR02353; NRPS_term_dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 3.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:KPI17813.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000037991};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 648..674
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 686..711
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 890..910
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 916..939
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 323..397
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1101 AA; 116272 MW; FC8E163B91C85303 CRC64;
MDAEAELFLA EEPIAPGDRV MAGLSVAFDA SCEEMWLAWR HGACLVPVPR SQVRSGADLG
PWLVEQEISV VSTVPTLAAL WEPEALNDVR LLIFGGEACP PELVQRLVTE GREVWNTYGP
TEATVVACAA LLTGEEPIRI GLPLNGWELA VVDEAGDPVP MGDSGQLVIG GVGLARYLDP
EKDAEKYAPL DSLGWARAYR SGDLVKAEPE GLIFLGRADE QIKLGGRRIE LGEVDAALQA
LPGVAGAAAA VRTARSGNQL LVGYVVTAEG WDQAAAVAKL RAELPAALVP LLAPVDDLPT
RTSGKVDRGA LPWPLEDVET PSAELYGTEA WLAEQWTEVL GIPVGGADDD FFAIGGGSLA
AAQLTTRLRT RYPSAAVLDI YQRPTLRKLA RHLEESAQDD GARRTVAPVP LRAKLVQLAL
LVPLCTILGL RWAVPLAALG NLAGSSYPWL PTAPWWAVAG AAVLFFSPPG RLAISAGGAR
LLLRGLKPGR YPRGGSVHLR LWTAERLAEF SGATGLTGSW LERYARALGA KIGPDVDLHS
LPPVTGMLKL GRGAAVESEV DLSGHWLDGD RLEIGPVKIG AHAVVGTRSM LFPGARVGKR
AEVAPGSAVA GQVPTGQRWA GAPAVKLGKA KRNWPKDRPQ RGLFWRAMYG ATGFALTALP
VVAALAALLV TSVFVKPHAG LGEALAQAFV ALVPATLAFG LAYATLLLIA VRLLSLGLRE
GTHPTHSRIG WQAWTVTQLM DRSRETLFPL YAGLITPVWL RLLGMRIGRG AEVSTVLALP
SLTTVGEDAF LADDTLTAPY ELGGGWVHVG RAEIGRRAFL GNSGMTAPGR SVPDGGLVGV
LSATPKKAKK GSSYLGLPPV KLPRAAQGGD QSRTYAPPAR LLWARGVVEL CRIVPVFCSA
GLAVLTVAAL SRLGGWAAWL LSGVVLLAAG TAACVLSVVA KWALVGRHRA GEHPLWSGFV
WRNELADTFV EVVAVPWLAG AVPGTPVLNL WLRGLGARIG KGVWVESYWL PETDLVTLED
AATVNRGCVL QTHLFHDRIL RTDTVVLREG ATLGPGGIVL PGSAIGARTT LGPASLVMAA
ESVPDDTRWL GNPIEAWRSG A
//
