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Database: UniProt
Entry: A0A0N1PF50_PAPXU
LinkDB: A0A0N1PF50_PAPXU
Original site: A0A0N1PF50_PAPXU 
ID   A0A0N1PF50_PAPXU        Unreviewed;      2362 AA.
AC   A0A0N1PF50;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   10-MAY-2017, entry version 12.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor {ECO:0000313|EMBL:KPJ04581.1};
GN   ORFNames=RR46_01024 {ECO:0000313|EMBL:KPJ04581.1};
OS   Papilio xuthus (Asian swallowtail butterfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Lepidoptera; Glossata; Ditrysia;
OC   Papilionoidea; Papilionidae; Papilioninae; Papilio.
OX   NCBI_TaxID=66420 {ECO:0000313|EMBL:KPJ04581.1, ECO:0000313|Proteomes:UP000053268};
RN   [1] {ECO:0000313|EMBL:KPJ04581.1, ECO:0000313|Proteomes:UP000053268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPJ04581.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KPJ04581.1};
RX   PubMed=26354079; DOI=10.1038/ncomms9212;
RA   Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA   Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y.,
RA   Jiang X., Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G.,
RA   Kronforst M.R., Wang W.;
RT   "Outbred genome sequencing and CRISPR/Cas9 gene editing in
RT   butterflies.";
RL   Nat. Commun. 6:8212-8212(2015).
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DR   EMBL; KQ458883; KPJ04581.1; -; Genomic_DNA.
DR   Proteomes; UP000053268; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR000493; InsP3_rcpt-bd.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SUPFAM; SSF100909; SSF100909; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053268};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:KPJ04581.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053268};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1869   1899       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1911   1930       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1956   1976       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1996   2020       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2066   2088       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2180   2203       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       79    233       RYDR_ITPR. {ECO:0000259|Pfam:PF01365}.
FT   DOMAIN      788    925       RYDR_ITPR. {ECO:0000259|Pfam:PF01365}.
FT   DOMAIN     1563   1669       RIH_assoc. {ECO:0000259|Pfam:PF08454}.
FT   DOMAIN     2003   2209       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED     2305   2339       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2362 AA;  266687 MW;  EC1D9E5CA3259A62 CRC64;
     MFYIYVKFPI DKEEEKPVMS KVGCSIVKED KEAFALISVS PSEVRDLDFA NDACKVLSAL
     STKLHHGNIE HNEMKALTCL LQDIVYFIAG FENEPNKSKA LDLVVENPNR DRQKLLREQY
     ILRQLFKILQ GPFQETSEGG GEPFLKIEEL YDPRYAPYKC IFRLCYRILR LSQQDYRKNQ
     ATKHFGFMQK QIGYDILAED TITALLHNNR KLLEKHITAS EIETFVGTLV STKYERSSEA
     EETGDKYTVE DEVMLLWNNK KCSRLLSELA TEARLEPRSE AAAILDYYRH QLDLFSNMCL
     NRQYLALNSL SAQLHIDLIL KCMSNASLSQ ELRASFCRLM LHLHVDRDPQ EPVTPVKYAR
     LWSDVSDTIH VHDYQCVKGG ADATREKVKA QFASTIRFVE NYLCRVVTST WYFSDHDQNK
     LTFEVVKLAR ELIYFGFYSF SDLLRLTKTL LSILDCVTAM DLLNETSPLA GEVESEGGVL
     RSIGDMGAVM TSITLGSVAR NVSTQTLVDQ LVYWPPCTLS PLTVLLFTRC PVLSTSPVGS
     GNGGGVQGSP SALALARKHP LVMETKLKII EILQFILDVR LDYRISCLLS IFKKEFEQSS
     ERQADSLARA DVEAIGLQAE GIFSCRDGLD LDECGGRMVL RVLLQLCSQG ASAALVSGAL
     ALLFRHFSQR QEVLAAFKQV QLLVSDADVE SYKQIKADLD VLRQSVEKSE LWVFNKGRAG
     ALDDHTELKG TVGPGGAVLE RNASLDNVLD TSRATKYDHM HEYEKIKEIL QRMIKYCTQG
     NSGGGDTGKP RRHEQRLLRN IGVHNIVLDL LQVPHDEDDA AMDELLALAH EFLQRFCHGN
     QQNQAILHKH LDLFLNAGIR EAQTVCAIFE ENPALCAHEG NDKVAAHFVH CIETRGRRPA
     YLHFLRTIVR AAGQHIRRSQ DLVMQEARIH CIETRGRRPA YLHFLRTIVR AAGQHIRRSQ
     DLVMQEMVNA GEDVLVFYND KVSFNYFIQM MRQYKQTNEM PEALRYHIQL VKLLTCCTLG
     KNVYTEIKCH SLLPLDDIVA TITHPDCIPE VKEAYVGFLN HCYIDTEVEM KEIYSSNYMW
     DLFERSFLQD MQAILHSDAT AYAMPSTSTD EVFSPQKSCA SSTQRAWLAY VTDVLMHTIC
     TFFNSPFSDQ STTVQTRQSI FVKLLQTTFR IYQCPWLTPP QKLNVEKCIR TLSEVAKSRS
     IAIPLELEAK IQTVFEKAAA LSRQTSKWLQ ASKTSKLEKM ASQSNLQNDR SVMEGLQEIV
     CLLEEQLRPL LQAEQSLLVD ILYRPHRLFT GPGELAHPDT SGIFISRLIR HTEKLLEEKE
     EKLCVKVLRT LREMMAVDPE YGEKGNQLRN KLLSQYFVNR KSEAKIQPPQ PPPVATHGPG
     AKVLLRTGQT LSQVQAHLDR EGASDLVVEL VINSVNRPAI FLEAIQLGIA LLEGGNPIIQ
     RSIFTKLQNG EISQSFLKVF YDKMRESQQE IRSLATSSTA SAGADKRASP TDKQKPIATE
     GKPSPGPIVV GEDMDDEITN ACGSAVHAYS DIHTMSHGTT VLEEIMSEKK RETSNSDVLP
     PKVAVMRPIL RFLQLLCENH NPDLQNLLRN QNNKSNYNLV SETLMFLDCI CGSTTGGLGL
     LGLYINEGNV ALINQTLETL TEYCQGPCHE NQNCIATHES NGLDIITALI LNDINPLGKT
     RMDLVLELKN NASKLLLAIM ESRNDSENNA ERILYNMNPE QLVDVACSAF NQEHAMDADS
     DSEDDAPVQG VSPKEVGHNI YILCHQLAGH NKELAALVRA TPSGVNAPAL QYYRTHTAQI
     EIVRTDRSME QIVFPIPEIC EYLPADSKHR VLQTAERDDQ GSKVADFFSR LDNLFHEMKW
     QKKLRGQPFL FWVSSYMSLW SNILFNFAVL INVIVAFFYP FQEENPKLGQ HLSLVVWCVS
     LAAGTLVACL PRSSGARALL ASAIVRLIYS AGPEPTLWAL GMLTIVVKGI HLVSIMGNQG
     TLSKSTRNVI TDPELLYHSV YLWFCFLGIC CHPFFFSVLV STNISQIDPF KLFVFEKGFD
     LLLDIVYREE TLLNVMRSVT RNGRSILLTA VLALVLVYMF SIVGYMFFRD HFLLNVDRLD
     DDDDPRFEER CDSNPASKYQ RAPRFVSVGG SLRERSCDSL IMCIVTTLNQ GLRNGGGIGD
     ILLAPASFEP LFVARVVYDL LFYFVVIVIV LNLIFGVIID TFADLRSEKQ QKELILKNTC
     FICGLNRSAF DNKTVSFEEH IKSEHNMWHY LYFMVLVRVK DPTEFTGPES YVHSMIKSNN
     LDWFPRLRAL SQMGGGEGDG GEVELRALQA QLERAQSAVR TLTDLLTELR DQMTEQRKQK
     QRIGLLNSTS AYLQNLQMNL PP
//
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