ID A0A0N4SUP9_MOUSE Unreviewed; 496 AA.
AC A0A0N4SUP9;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Membrane associated guanylate kinase, WW and PDZ domain containing 1 {ECO:0000313|Ensembl:ENSMUSP00000144769.2};
GN Name=Magi1 {ECO:0000313|Ensembl:ENSMUSP00000144769.2,
GN ECO:0000313|MGI:MGI:1203522};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000144769.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000144769.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000144769.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000144769.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000144769.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A0N4SUP9; -.
DR SMR; A0A0N4SUP9; -.
DR ProteomicsDB; 355263; -.
DR Antibodypedia; 15389; 214 antibodies from 26 providers.
DR Ensembl; ENSMUST00000204532.3; ENSMUSP00000144769.2; ENSMUSG00000045095.17.
DR AGR; MGI:1203522; -.
DR MGI; MGI:1203522; Magi1.
DR VEuPathDB; HostDB:ENSMUSG00000045095; -.
DR GeneTree; ENSGT00940000155820; -.
DR ChiTaRS; Magi1; mouse.
DR Proteomes; UP000000589; Chromosome 6.
DR Bgee; ENSMUSG00000045095; Expressed in ventricular zone and 236 other cell types or tissues.
DR ExpressionAtlas; A0A0N4SUP9; baseline and differential.
DR CDD; cd00992; PDZ_signaling; 2.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR10316; MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED; 1.
DR PANTHER; PTHR10316:SF12; MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF16663; MAGI_u1; 1.
DR Pfam; PF00595; PDZ; 2.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00228; PDZ; 2.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS50106; PDZ; 2.
DR PROSITE; PS01159; WW_DOMAIN_1; 2.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:A0A0N4SUP9,
KW ECO:0007829|PeptideAtlas:A0A0N4SUP9};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 73..106
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 132..165
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 237..306
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 408..486
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 496 AA; 54412 MW; E8333481652B5776 CRC64;
MQNAGIVHPE NEEEEDVPEM NSSFTADSGD QDEHTLQEAT LPPVNSSILA APITDPSQKF
PQYLPLSAED NLGPLPENWE MAYTENGEVY FIDHNTKTTS WLDPRCLNKQ QKPLEECEDD
EGVHTEELDS ELELPAGWEK IEDPVYGVYY VDHINRKTQY ENPVLEAKRK KQLEQQQQQQ
QPQPPQPEEW TEDHASVVPP VAPSHPPSNP EPARETPLQG KPFFTRNPSE LKGKFIHTKL
RKSSRGFGFT VVGGDEPDEF LQIKSLVLDG PAALDGKMET GDVIVSVNDT CVLGHTHAQV
VKIFQSIPIG ASVDLELCRG YPLPFDPDDP NTSLVTSVAI LDKEPIIVNG QETYDSPASH
SSKTGKVSSM KDARPSSPAD VASNSSHGYP NDTVSLASSI ATQPELITVH IVKGPMGFGF
TIADSPGGGG QRVKQIVDSP RCRGLKEGDL IVEVNKKNVQ ALTHNQVVDM LIECPKGSEV
TLLVQRGATG EERQPE
//
