ID A0A0N4T6X2_BRUPA Unreviewed; 536 AA.
AC A0A0N4T6X2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=BTB domain-containing protein {ECO:0000313|WBParaSite:BPAG_0000395901-mRNA-1};
GN ORFNames=BPAG_LOCUS3923 {ECO:0000313|EMBL:VDN85109.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000395901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0000395901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN85109.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex which mediates the ubiquitination and subsequent
CC proteasomal degradation of target proteins. May have a role in synapse
CC differentiation and growth. {ECO:0000256|ARBA:ARBA00043912}.
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DR EMBL; UZAD01001495; VDN85109.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4T6X2; -.
DR STRING; 6280.A0A0N4T6X2; -.
DR WBParaSite; BPAG_0000395901-mRNA-1; BPAG_0000395901-mRNA-1; BPAG_0000395901.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 6.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 2.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..40
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 536 AA; 59519 MW; 266E67FBA80EF6BC CRC64;
MFTSEMAESR QQEIQMVDIE PRTLQGLINF CYTGEITIAD FNVQSILPAA CLLQLGEVQE
VCCEFLKKQL DATNCLGIRA FADTHACRDL MRIADKFTHH NFQDVAKSEE FISLPADQLI
NIISSEELNV RSEEVVFRAA MAWIRHDLPN RRQFLPKVLE HIRLPLCPAK FLVSVVSEDP
LIKIDAQCRD LVDEAKNYLL LPLERPNMQG PRTRSRKPLR YGEVLYAVGG WCSGDAIASV
ERMDGRTGEW RCVAPMSKRR CGVGVAVLDN LLYAVGGHDG QSYLNSVERY DPATNQWSSD
IAPTSTCRTS VGVAVLGGLL YAIGGQDGVC CLNVVERYDA HRNEWAEVAP MSTRRLGVSV
SVLNGCLYAV GGSDGQNPLN TVERCVAASV GYDSRINKWM TVKPMNTRRK HLGTAVHDGC
LYAVGGRDNA CELSSAEKYD PNTNEWVNVV AMNNRRSGVG LAVVNDQLYA VGGFDGTTYL
KTVEVYDRET NQWRQSGCMT YRRLGGGVGV VRLDHDQYVP FSLDPDLTPF DDPPLM
//
