ID   A0A0N4T705_BRUPA        Unreviewed;       260 AA.
AC   A0A0N4T705;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=SpoU_methylase domain-containing protein {ECO:0000313|WBParaSite:BPAG_0000399201-mRNA-1};
GN   ORFNames=BPAG_LOCUS3956 {ECO:0000313|EMBL:VDN85142.1};
OS   Brugia pahangi (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000399201-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:BPAG_0000399201-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDN85142.1, ECO:0000313|Proteomes:UP000278627}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAD01001532; VDN85142.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4T705; -.
DR   STRING; 6280.A0A0N4T705; -.
DR   WBParaSite; BPAG_0000399201-mRNA-1; BPAG_0000399201-mRNA-1; BPAG_0000399201.
DR   Proteomes; UP000038020; Unplaced.
DR   Proteomes; UP000278627; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0016423; F:tRNA (guanine) methyltransferase activity; IEA:InterPro.
DR   GO; GO:0030488; P:tRNA methylation; IEA:InterPro.
DR   CDD; cd18091; SpoU-like_TRM3-like; 1.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR045330; Trm3/TARBP1.
DR   InterPro; IPR044748; Trm3/TARBP1_C.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR12029:SF11; METHYLTRANSFERASE TARBP1-RELATED; 1.
DR   PANTHER; PTHR12029; RNA METHYLTRANSFERASE; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   SUPFAM; SSF75217; alpha/beta knot; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..260
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5033720529"
FT   DOMAIN          107..249
FT                   /note="tRNA/rRNA methyltransferase SpoU type"
FT                   /evidence="ECO:0000259|Pfam:PF00588"
SQ   SEQUENCE   260 AA;  29093 MW;  F48E92207DE51AA3 CRC64;
     MYLAIFKVLF SSIQILTVLT ILPEKVGLTA QDAIMSHLLK CISMDDFACV HRDSDNLSQY
     PSFVFGQTQV QRHQQIHEPD GLSDMSVIQR KFNAVSVNRA LLEGVSLIVV ASLLDKAANL
     GGICRTCEVL GVEKLIVADL AKIKDRDFMA LSMSSENWMN LEESRPEELP NLLLSFRNSG
     YVIIGAEQTT NSTPLHKIRF PSKMVLLLGN EKEGIPMHLL SYLDKTVEVL QIGHTRSLNV
     HVTGALLIYR FFEEFIATKT
//