ID A0A0N4TD80_BRUPA Unreviewed; 225 AA.
AC A0A0N4TD80;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=HECT domain-containing protein {ECO:0000313|WBParaSite:BPAG_0000616801-mRNA-1};
GN ORFNames=BPAG_LOCUS6131 {ECO:0000313|EMBL:VDN87317.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000616801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0000616801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN87317.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00104}.
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DR EMBL; UZAD01005191; VDN87317.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4TD80; -.
DR STRING; 6280.A0A0N4TD80; -.
DR WBParaSite; BPAG_0000616801-mRNA-1; BPAG_0000616801-mRNA-1; BPAG_0000616801.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR044611; E3A/B/C-like.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR PANTHER; PTHR45700:SF8; HECT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 46..214
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
SQ SEQUENCE 225 AA; 25420 MW; D41716B38F73CAF4 CRC64;
MQISMSTSGI MILPFNISLQ PHPFFEISVH RDNIVDDAMI ALLSSKHMDL KKPLKVYFIG
EEADDAGGVK KEFFMLLFQE LLQAKYGMFT ENEESHLIWF SGVETDPLSF KLVGMLCALA
IYNSVLVDFP FPLALYKKIL DVPLELEDLS ELSPAEGRSL RSLLDYEDDD IEEVFSLTFM
ISVSLLGDSK DIELKTNGAE IPVNQANKLE FVQVSPSFLF SLFFL
//
