ID A0A0N4TL78_BRUPA Unreviewed; 702 AA.
AC A0A0N4TL78;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Neurogenic locus Notch protein {ECO:0000313|WBParaSite:BPAG_0000912801-mRNA-1};
GN ORFNames=BPAG_LOCUS9090 {ECO:0000313|EMBL:VDN90276.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000912801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0000912801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN90276.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; UZAD01013146; VDN90276.1; -; Genomic_DNA.
DR STRING; 6280.A0A0N4TL78; -.
DR WBParaSite; BPAG_0000912801-mRNA-1; BPAG_0000912801-mRNA-1; BPAG_0000912801.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 11.
DR Gene3D; 2.10.25.10; Laminin; 17.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR12916; CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2; 1.
DR PANTHER; PTHR12916:SF4; NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1-RELATED; 1.
DR Pfam; PF00008; EGF; 8.
DR Pfam; PF07645; EGF_CA; 3.
DR Pfam; PF12661; hEGF; 3.
DR PRINTS; PR00010; EGFBLOOD.
DR PRINTS; PR01983; NOTCH.
DR SMART; SM00181; EGF; 17.
DR SMART; SM00179; EGF_CA; 16.
DR SUPFAM; SSF57196; EGF/Laminin; 10.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 11.
DR PROSITE; PS00022; EGF_1; 16.
DR PROSITE; PS01186; EGF_2; 13.
DR PROSITE; PS50026; EGF_3; 17.
DR PROSITE; PS01187; EGF_CA; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 22..58
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 60..95
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 100..137
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 139..175
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 177..215
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 217..253
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 254..292
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 294..332
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 334..370
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 386..418
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 420..458
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 460..496
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 498..534
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 536..574
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 576..613
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 615..651
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 653..689
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 48..57
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 64..74
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 85..94
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 127..136
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 165..174
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 205..214
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 243..252
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 263..280
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 282..291
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 322..331
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 360..369
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 408..417
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 429..446
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 448..457
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 486..495
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 524..533
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 545..562
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 564..573
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 603..612
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 641..650
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 679..688
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 702 AA; 77452 MW; 9B6293D75D1E0FBF CRC64;
EISKISECKC LYLFFAGERC DRRNYCEGNP CRNGGSCIST TGGYRCGCPE GFHGNKCELD
INECHLNPCV RGKCINEFGS YRCDCPHDFT GRNCETFSFN IDPCSTSPCH NNAKCYTYRD
KYYSCECRPG FTGRHCEVNI DDCSENACMN GGTCIDREQG YECKCPPFYT GRLCEEDIDE
CELGLHECKN GATCFNKKEG YQCVCVNGWE GIHCEINKDD CKDALCEAGS TCVDHLAKYT
CECPPGRIGL LCHMEDPCLS NPCQVGSVCE PDTSSGKYTC ECPKGYTGED CSNDINECNQ
DHAVCYNGGT CVNTPGSFHC ECPPGYTDWH CQTHVNQCST NPCLNSGTCL DYGTRFKCVC
MSGFHGKRCE LHCPSGYEGE NCERRQYIEC SITDCLNGGV CSKGSCRCPP GFTGDRCEKK
LDPCKYHNCP QNAICIPINN SVTYKCECKL GFYGHDCKLE MNECASNPCQ HGGVCTDHLN
GYVCSCSAGY TGEQCQTNID DCIHHPCLHG GTCIDGINSY SCHCALPYDG DRCQYELDPC
RTNRCENGAF CKPTPTYRNY TCSCTNGFYG YYCDTDIDEC AVNNPCLNGG TCANKFGSYH
CRCSDGYTGR NCENDRNDCL PNPCLNGGHC MDELNGYHCE CLAGFTGRQC ATNINECESS
PCENGASCID HINGFECICR RGFSGTFCQT NDDDCQPGYN KA
//
