ID A0A0N4TPM7_BRUPA Unreviewed; 356 AA.
AC A0A0N4TPM7;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 2.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Glutathione transferase {ECO:0000313|WBParaSite:BPAG_0001051101-mRNA-1};
GN ORFNames=BPAG_LOCUS10473 {ECO:0000313|EMBL:VDN91659.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0001051101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0001051101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN91659.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GST superfamily. Omega family.
CC {ECO:0000256|ARBA:ARBA00011067}.
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DR EMBL; UZAD01013188; VDN91659.1; -; Genomic_DNA.
DR STRING; 6280.A0A0N4TPM7; -.
DR WBParaSite; BPAG_0001051101-mRNA-1; BPAG_0001051101-mRNA-1; BPAG_0001051101.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0045174; F:glutathione dehydrogenase (ascorbate) activity; IEA:UniProt.
DR GO; GO:0004364; F:glutathione transferase activity; IEA:InterPro.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR040079; Glutathione_S-Trfase.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR005442; GST_omega.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43968; -; 1.
DR PANTHER; PTHR43968:SF9; GST N-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13417; GST_N_3; 1.
DR PRINTS; PR01625; GSTRNSFRASEO.
DR SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR SFLD; SFLDG00358; Main_(cytGST); 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS50405; GST_CTER; 1.
DR PROSITE; PS50404; GST_NTER; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 132..210
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
FT DOMAIN 215..339
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
SQ SEQUENCE 356 AA; 41321 MW; F5A5B3B471592C98 CRC64;
MSFNRIPAVT SLLYFCYNIF TLYRMLWIRK LKVAFFSVQL IILCSYETMG QINETFNSES
LSMLSIMDEV FPNVPNRNQR RFANTTDLRK GIIKNRTWSE GVAQLLPRSI NIRGLNSLAL
HRDSPEPYSG LGTIRLYSMR FCPYAERAII YLARKRLQVE ITNINPENVP KWFLNKSPLG
RVPTFEMNGI TIYESSVIAE YLDEIFPETA ILPRHPVAKA NQKILVERMS PLISTMFKIL
HPNNVTVQQD VDKSLHNALR NAEVLLTDDF YGGKILGFAD IMMWPFLERL QLVTVNPYTE
FRYFPGFYYP KISAYMARMQ RQPEILFAQR PIEQHAAYVN SFLTGHPNYD IGINQS
//
