ID A0A0N4TSU2_BRUPA Unreviewed; 694 AA.
AC A0A0N4TSU2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=PRP18 homolog {ECO:0000256|ARBA:ARBA00031388};
GN ORFNames=BPAG_LOCUS11742 {ECO:0000313|EMBL:VDN92928.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0001178001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0001178001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN92928.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAD01013246; VDN92928.1; -; Genomic_DNA.
DR STRING; 6280.A0A0N4TSU2; -.
DR WBParaSite; BPAG_0001178001-mRNA-1; BPAG_0001178001-mRNA-1; BPAG_0001178001.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0042811; P:pheromone biosynthetic process; IEA:UniProt.
DR GO; GO:0008380; P:RNA splicing; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR Gene3D; 1.20.940.10; Functional domain of the splicing factor Prp18; 1.
DR Gene3D; 4.10.280.110; Pre-mRNA processing factor 4 domain; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR InterPro; IPR004098; Prp18.
DR InterPro; IPR014906; PRP4-like.
DR InterPro; IPR036285; PRP4-like_sf.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR Pfam; PF02840; Prp18; 1.
DR Pfam; PF08799; PRP4; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SMART; SM00500; SFM; 1.
DR SUPFAM; SSF47938; Functional domain of the splicing factor Prp18; 1.
DR SUPFAM; SSF158230; PRP4-like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
PE 4: Predicted;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000278627}.
FT DOMAIN 93..143
FT /note="Pre-mRNA processing factor 4 (PRP4)-like"
FT /evidence="ECO:0000259|SMART:SM00500"
SQ SEQUENCE 694 AA; 80326 MW; 3AEA241ECD60EB2F CRC64;
MDNRIDRGTQ RDMDILRAEI ERKRKQFEGI QAPNKYLKRS QLLQKGEEKN REYHQAKPLA
PTPVTAARSG GLARIENQTK EMFTEPELDC VDLPRVDVIK RLRSRSQPIT LFGETEQESR
ARLRKLEIEQ PDMKEGWKND FQSAMKEVDH ELIEEVIKGE QYSAGKHDVA MPNSAGDNNW
ERIEANAELL GEGDNPNRDC DVIREFFSYI LTRWGKALNA RDEVEKRHTI FSSFLTIGFY
GKSAEGKLAA TMHKQTMEHL RPLMKNLEKH NVNADIREHL IKICRLIIID RDYIRANNAY
MEMAIGNAPW PVGVTRSGLH QRPGSAKAYV SNIAHVLNDE TQRKYIQAFK RIMTRCQKYF
PTDPSKCVEY VREIETALFS TQLSFLCEMA DDVAQLLAPY QYILKLPGKQ LRSQLAKAFN
FWLQVDVEVL DSIMTVVEML HNASLMIDDI EDSSLLRRGL PVTHSIYGIA RTINTANYVY
FAALSRCILL GKFEAVEIFT EQLLELHRGQ GKELYWRDIV QCPTEEEYEQ MAMQKTGGLF
ALTVQLMELF GKKQYDFKSL IKNLAIYFQI RDDYINLCSR TYAEQKTFAE DLTEGKFSFP
IIVAIDKKYN DDEIINILRQ RPKDVEVKKY CIRIIEERGA FGYTLKRLQE LHDLLISHID
MLGGNKELKI LIETLHEDIQ PVRKVGNMKM SNGK
//
