ID A0A0N4TTL0_BRUPA Unreviewed; 669 AA.
AC A0A0N4TTL0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=INCENP_ARK-bind domain-containing protein {ECO:0000313|WBParaSite:BPAG_0001208001-mRNA-1};
GN ORFNames=BPAG_LOCUS12042 {ECO:0000313|EMBL:VDN93228.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0001208001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0001208001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN93228.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the INCENP family.
CC {ECO:0000256|ARBA:ARBA00010042}.
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DR EMBL; UZAD01013266; VDN93228.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4TTL0; -.
DR STRING; 6280.A0A0N4TTL0; -.
DR WBParaSite; BPAG_0001208001-mRNA-1; BPAG_0001208001-mRNA-1; BPAG_0001208001.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR Gene3D; 6.10.250.2990; -; 1.
DR InterPro; IPR005635; Inner_centromere_prot_ARK-bd.
DR PANTHER; PTHR13142; INNER CENTROMERE PROTEIN; 1.
DR PANTHER; PTHR13142:SF1; INNER CENTROMERE PROTEIN; 1.
DR Pfam; PF03941; INCENP_ARK-bind; 1.
PE 3: Inferred from homology;
KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000278627}.
FT DOMAIN 563..619
FT /note="Inner centromere protein ARK-binding"
FT /evidence="ECO:0000259|Pfam:PF03941"
FT REGION 183..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 361..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 264..311
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 669 AA; 76704 MW; 1E48B6709D63ECAF CRC64;
MCETLETFTE KTYYQHRLTM IIESDVNGLL SNSRVNFCHI DQLIVCKFDE NILSKINNFF
LWLEEQKDIG KEIIRNETGR TRLPKTPKRG YCFSQEAETF QKCRKRLLDS VKRKGAAIFA
NDGNTALCAV QTPKSSRNAT ARAVKQETML AGQMNGRKMP IPPVPAPRQY VPKQQTPIKV
NKYPSVTTSS NNTPKRTPLR NGMTPKITTQ KTLVNSEATA RKITVTPKAT VQRTAVTPKM
ADKNITITPK AIIQQPTFKR SEVIRKMEKR TNNVIKNKEE LMKEKAERAR RDREERALRV
KMNNKKKEEE ALEKLRIIKM REQQIEELRQ KQRVPQRAIS KSPCRTRAYY NRIQKPLVRA
KSSQDISVSK SASQTKMTND TQENLQLQGK RNYVDSIKQD IDFQNKRQKM ESVDCSETDN
TDRHSIKTDM LEKVLSEEPV DVHIHTECPE SDEKRISEDK GNSQNTIYVN SDSNETTAII
EQEILGSLRN CDVSPDIVLH SPVVESSEIN EKENVDEASQ VMEVDNLTAE TSSINNQTFD
KSLNVSENET LDDIGNNYDV ESISSNDETD DEENPRKPIP LWAQGERLQN ALQKQVVQPS
IDADAYFGPV RTPMLNKIFA RNRTRYNKRT SSALWTSPMS NPKKGTSKFF ELQSVKYGNK
SRYHDELLK
//
