ID A0A0N4U3T5_DRAME Unreviewed; 706 AA.
AC A0A0N4U3T5;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=G_PROTEIN_RECEP_F3_4 domain-containing protein {ECO:0000313|WBParaSite:DME_0000139801-mRNA-1};
OS Dracunculus medinensis (Guinea worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000139801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:DME_0000139801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A0N4U3T5; -.
DR WBParaSite; DME_0000139801-mRNA-1; DME_0000139801-mRNA-1; DME_0000139801.
DR Proteomes; UP000038040; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR CDD; cd06366; PBP1_GABAb_receptor; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR002455; GPCR3_GABA-B.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR PANTHER; PTHR10519:SF76; GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR PRINTS; PR01177; GABAB1RECPTR.
DR PRINTS; PR01176; GABABRECEPTR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..706
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005886385"
FT TRANSMEM 451..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 529..549
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 576..597
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..657
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 672..693
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 522..696
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 706 AA; 79646 MW; BA6A085CB9143967 CRC64;
LWGCVMLLER LLIIATMVDS VFSIDLHIGG VFPMEAGSGG WAGGQACLPA VQMALRDVNA
NRNILMGYNL VLHHHNSKCQ PGLAAKQLYE LLYRSPTKLI LLAGCSPVTT IIAEAAPVWN
LIVLSYGGSS PALSNRKRFP TLFRTHPTAN MQNPTRIKLF HKFKWKRITV LQSVEEVFTS
TAKDLENQCR DSGIRIERQS FYGDPTDAIK TLVRQDARII VGLFYVTEAR RVLCQAYRHG
LYGRKYVWFF IGWYADTWFI PPPEEPVNCT VEQMTIAAQY HITTESIMLS KNEQKTISGM
TGFEFQQKLM DIIKTDPANT GGFPEAPLAY DAVWAIALAF NCTLTRLSNS QTLADFTYNN
TVIANKLFNC VKNTQFKGVS GQVMFSDLGD RIARTQIEQL QDGKYEMLGT YDTTTSHLDW
YGKEKFATLN GLAPPDSTII KESFLTISIE LYYAVAAFAI IGIFLSITIF IFNFKNSSRS
IIIQSQPKCN NIFIVGCILC SFSLLLMGIP ADGITLPKES FTFLCHTRIS LLMVGFTFGY
GSMFAKVWIV HRVGASGNQE LVSQQKSNDP ISSKKFYLII AIFFIIDLII IVCWLLYDPL
QREERRFPLQ EPPPGTEEDV MLLPILEYCQ SKRHEIWTGI IMGYKCLLLI FGLFLAYESR
NLKLRYINDS RFVGLAIYNV TILSLVTGPV SWIDIYSKSP SFKPVH
//
