ID A0A0N4V7Y8_ENTVE Unreviewed; 568 AA.
AC A0A0N4V7Y8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000313|WBParaSite:EVEC_0000643101-mRNA-1};
OS Enterobius vermicularis (Human pinworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000643101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EVEC_0000643101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A0N4V7Y8; -.
DR WBParaSite; EVEC_0000643101-mRNA-1; EVEC_0000643101-mRNA-1; EVEC_0000643101.
DR Proteomes; UP000038041; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR PANTHER; PTHR45638:SF11; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 30..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 362..480
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 568 AA; 66164 MW; AD665053E4417196 CRC64;
LSKFDLYSGE DNNFFRSLLL GPVDPTSTIY LFWLAATAFA TFYNTIAVVA FIFDDIRYNL
FYHWLCCNAV CDLIYLFDIY VQARKGSLNN GEVEKDVKKT AKCYFKRYPN LMPTDLLLLL
FSNVSLSRLN RLFKFYRLWE FAERAQMRTQ WPNSFKIFSL IVLCLILFHW NACAYFYISL
ITDIDINGKK QQRISLFRSH LFLFLISSVV FEKGDTKIGK KLSRELVFSN FSKEYSLSFY
WSSLTLTTKG QQPYPTDSEQ NWLEIIDTLI GLLVFATIVG SVGAVVLMMS RKQAEFQQLL
DGIKFYMNYR NVTPEIQKRV INCCEYVRDQ NIISQTENII ETLPTRLQGE LAVQLHLQTL
NLVQDCEAGL LYELLLRLRY QLYSPGDLLC KRGDLAREMY IIERGRLNCV SDDGGEIYRV
LEAGDVFGQL AILNLSGDIS GNRREVALCA AAYTDIYSLH QDDAMEVLQD YPEERRKLIK
REDYLILSEM LLCNKFKKQE KKATVTNAFA GIELLKFERL YDPVLADHRT DEWKMLCREE
QLIEVGKFLD EIEKGLDDLY QDFNVKNF
//
