ID   A0A0N4VAC0_ENTVE        Unreviewed;       904 AA.
AC   A0A0N4VAC0;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Rho-GAP domain-containing protein {ECO:0000313|WBParaSite:EVEC_0000740801-mRNA-1};
GN   ORFNames=EVEC_LOCUS6929 {ECO:0000313|EMBL:VDD92178.1};
OS   Enterobius vermicularis (Human pinworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX   NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000740801-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:EVEC_0000740801-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDD92178.1, ECO:0000313|Proteomes:UP000274131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UXUI01008702; VDD92178.1; -; Genomic_DNA.
DR   STRING; 51028.A0A0N4VAC0; -.
DR   WBParaSite; EVEC_0000740801-mRNA-1; EVEC_0000740801-mRNA-1; EVEC_0000740801.
DR   Proteomes; UP000038041; Unplaced.
DR   Proteomes; UP000274131; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR46150; RHO GTPASE-ACTIVATING PROTEIN 100F; 1.
DR   PANTHER; PTHR46150:SF3; RHO GTPASE-ACTIVATING PROTEIN 100F; 1.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00239; C2; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000274131}.
FT   DOMAIN          498..622
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          655..860
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          98..117
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          170..206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          284..315
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          881..904
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        301..315
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   904 AA;  101303 MW;  34231F9127013714 CRC64;
     MFFYDXXXXX XXXXXXXXFG ENSELAKFGD VLHPGDEILS VNNVDVSSMS IDDVVLVLSI
     PRRLLLRTRF FKNQRERLPQ SQSTLSRPVV VFHKEVEEKS ENADDASTST LLSHPTSTAN
     TWLGKKARKQ QQVNFFSQLG CQAWSQLEMI KHCPQPSCST TALPSAMATI RRPQPPARSV
     KLYDSKLDPR PQPSRTPQPY QNYGYSLTRS RPLQRPQMVM EPRIFASGSG ISPQVYSTQS
     YEPADTSNYS VPYRSDATDT SIKIQPRSMS DVAGYTSTLH RTGYSSAGDR IRPGTVGLSG
     WEPPTTFSSK SNSLPRRRAV PDSLQRTVKW RNDVTGGLNY TPGAESDGAI SAPENLLSPT
     LTRPYFLRRG SGAHSLIKMI ALKQQTEFGR LKYELLNGFF KCFVGPRSGT SGQGRTIDDI
     FSAQEYRHWA DFILPPQERQ SRWSHAYGER QGASVRSSSL PSRTILSNVG RFSVGHEKGD
     LLDQLHVSPL MNRRVPLRPA GPGFDVDTLN VKSLTGMLIV QVIEGRGLKL PLRQKAFTEE
     MYCVLEVNEV HRARTGVSTA DQRYQWKETF QIDVQHATHI HFFVYSWHPQ YRHKLCHKGC
     LKLLEAFIVD RLNGNRMFAL NLEPKGQLIV RIAFNGMATV FKRTVNTRFN GVFGVPLQRL
     ITRDNRETPI ILSRLLQEIE DRGTDYSGLY ILSGSEEKKR VLRSELENNV EAADLSVDVV
     PDTNVLACLV KDFLRELPEP LIPISIYSML VDAFSVTLPN DPQGNQQLLL RIIDCLPTPN
     KKTLIQLMDH LRSVTQSDSY NGIAASRLTS IFGCLIFCSC DVRIEHPPSG TFSKDAINPL
     DPDQATRTLG MLLDNWPPRG WFQFYEFILA LAFIDYNTGS GSDSSGGSDS VEASAPNPVS
     ESQC
//