ID A0A0N4VE91_ENTVE Unreviewed; 398 AA.
AC A0A0N4VE91;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Kunitz/Bovine pancreatic trypsin inhibitor domain protein {ECO:0000313|WBParaSite:EVEC_0000899401-mRNA-1};
GN ORFNames=EVEC_LOCUS8435 {ECO:0000313|EMBL:VDD93684.1};
OS Enterobius vermicularis (Human pinworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0000899401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EVEC_0000899401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDD93684.1, ECO:0000313|Proteomes:UP000274131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; UXUI01009425; VDD93684.1; -; Genomic_DNA.
DR STRING; 51028.A0A0N4VE91; -.
DR WBParaSite; EVEC_0000899401-mRNA-1; EVEC_0000899401-mRNA-1; EVEC_0000899401.
DR Proteomes; UP000038041; Unplaced.
DR Proteomes; UP000274131; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00109; Kunitz-type; 2.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 3.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR PANTHER; PTHR24039; FIBRILLIN-RELATED; 1.
DR PANTHER; PTHR24039:SF38; PROTEIN CBR-MEC-9; 1.
DR Pfam; PF12947; EGF_3; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF00014; Kunitz_BPTI; 3.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00131; KU; 3.
DR SUPFAM; SSF57362; BPTI-like; 3.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 2.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 3.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01187; EGF_CA; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..398
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041160128"
FT DOMAIN 23..73
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 106..159
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 206..246
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 286..326
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 332..388
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
SQ SEQUENCE 398 AA; 45629 MW; 2283C00D40E42352 CRC64;
MLFAIFYFGL YFRSPLAQVY NPCNETEDPG PCQQFQVKWY WDKLDNKCKK FLYGGCLGNL
NRFDTKNQCI RQCLYELDNI DTIPDKKKAA QSCQNSAHVP SFLELCFLPP DKGECENYRT
GDRYYYFNAE AGKCEPFIYR GCAGNANRFY SLQKCRSVCA ERLSPHKIAC SKCDLRVSYC
KEYSKYNYTC ECREGYQKLS SGQCVDLNEC LKPSKLCDRN AQCYNTPGSY ICRCKPGYRG
NGKRCTFVGV GRSTLDCKRC SKNATCSHGV CTCKEGFVGD GFNCTDVDEC TRRPGMCDRN
AKCVNVAGSY ICECLPGFAG NGYFCTKKID ACLDKFDVEY QYQCGVEQWR EHYYYDHKTK
KCKLFWYDGC PGKSRNIFSK LHACELMCEF GHVLDRSG
//
