ID   A0A0N4W4P9_HAEPC        Unreviewed;       455 AA.
AC   A0A0N4W4P9;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=AB hydrolase-1 domain-containing protein {ECO:0000313|WBParaSite:HPLM_0000488101-mRNA-1};
GN   ORFNames=HPLM_LOCUS4873 {ECO:0000313|EMBL:VDO24190.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0000488101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0000488101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO24190.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO24190.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAF01016262; VDO24190.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4W4P9; -.
DR   STRING; 6290.A0A0N4W4P9; -.
DR   WBParaSite; HPLM_0000488101-mRNA-1; HPLM_0000488101-mRNA-1; HPLM_0000488101.
DR   OMA; THCTQLP; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   PANTHER; PTHR12277; ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR12277:SF72; PHOSPHATIDYLSERINE LIPASE ABHD16A; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        35..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        70..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          199..356
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
SQ   SEQUENCE   455 AA;  51331 MW;  A423A92F40A3FFD3 CRC64;
     MGRIYALLTG PRLYRVFGQP ERQPNVVESI GNYSILFSGL FYFSTSLAFS PVILILLYTR
     GALNIHTGLV VLKYATYLAV LFFFHNWTFK QLYLKALKRY DFDLEGVNAD FHAVRNENLY
     FHRGSSRDAW YAVHAFGRHM LYPGSVSLLN WLLGGSLLSA RNLMVSAKQG KRAWLRTTEG
     DLIDTMYIRG DDTPENRILV ITCEGNAGYY EIGIANTPAQ MGYSVLGWNQ PGFGQSSGLP
     FPNNTLAAAD AVMQYAQSEL GYHEENIVLF GWSIGGFPAS WLAANYPNVK AVILDATFDD
     VLPLAQARMP KVLSDVVKYA IRTHFDLNIK SIIAKYKGPL KLIRRLQEEI LTTDDTGTEA
     QRRASNRANF LLKSVIQQRH PALLVDLDSQ VDRWLAMTPQ HRAMAAHPKN DAEITIRRAR
     LFAACDHYLV DFDATHVQPL DPGYFNIPEP IRDLK
//