ID A0A0N4W559_HAEPC Unreviewed; 216 AA.
AC A0A0N4W559;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Guanylate kinase-like domain-containing protein {ECO:0000313|WBParaSite:HPLM_0000507301-mRNA-1};
GN ORFNames=HPLM_LOCUS5065 {ECO:0000313|EMBL:VDO24796.1};
OS Haemonchus placei (Barber's pole worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0000507301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HPLM_0000507301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO24796.1, ECO:0000313|Proteomes:UP000268014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHpl1 {ECO:0000313|EMBL:VDO24796.1,
RC ECO:0000313|Proteomes:UP000268014};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAF01016285; VDO24796.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4W559; -.
DR STRING; 6290.A0A0N4W559; -.
DR WBParaSite; HPLM_0000507301-mRNA-1; HPLM_0000507301-mRNA-1; HPLM_0000507301.
DR OMA; HIARGTE; -.
DR Proteomes; UP000038042; Unplaced.
DR Proteomes; UP000268014; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0004017; F:adenylate kinase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01428; ADK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00235; Adenylate_kinase_Adk; 1.
DR InterPro; IPR006259; Adenyl_kin_sub.
DR InterPro; IPR000850; Adenylat/UMP-CMP_kin.
DR InterPro; IPR007862; Adenylate_kinase_lid-dom.
DR InterPro; IPR036193; ADK_active_lid_dom_sf.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01351; adk; 1.
DR PANTHER; PTHR23359:SF254; ADENYLATE KINASE ISOENZYME ZK673.2-RELATED; 1.
DR PANTHER; PTHR23359; NUCLEOTIDE KINASE; 1.
DR Pfam; PF00406; ADK; 1.
DR Pfam; PF05191; ADK_lid; 1.
DR PRINTS; PR00094; ADENYLTKNASE.
DR SUPFAM; SSF57774; Microbial and mitochondrial ADK, insert 'zinc finger' domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..207
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
SQ SEQUENCE 216 AA; 24214 MW; 9C2E67601B515F7B CRC64;
MLRVLLSGPA GSGKNTIAKM LLKEFDQFGY FSAGDVIRDH IQRGTEFGQR AASFVRKGEL
IPDSIVSNVL LEEIRNAGNK LILNGYPRSM CQVKMIEEVA PLDLVVELKV PKKVLIDRLS
KQLVHHGSGR TYNLDFNPPK VEGKDDITGE PLFKRDDDAA EVVRRRLEVH EKTESKVVDY
YRNHGICVTM SGDKSSTVFH AVSEMITDLL KKRAFG
//
