ID A0A0N4W747_HAEPC Unreviewed; 440 AA.
AC A0A0N4W747;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Rho GTPase-activating protein 68F {ECO:0000313|WBParaSite:HPLM_0000592501-mRNA-1};
GN ORFNames=HPLM_LOCUS5917 {ECO:0000313|EMBL:VDO27454.1};
OS Haemonchus placei (Barber's pole worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0000592501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HPLM_0000592501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO27454.1, ECO:0000313|Proteomes:UP000268014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHpl1 {ECO:0000313|EMBL:VDO27454.1,
RC ECO:0000313|Proteomes:UP000268014};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAF01016408; VDO27454.1; -; Genomic_DNA.
DR STRING; 6290.A0A0N4W747; -.
DR WBParaSite; HPLM_0000592501-mRNA-1; HPLM_0000592501-mRNA-1; HPLM_0000592501.
DR OMA; PTRVREY; -.
DR Proteomes; UP000038042; Unplaced.
DR Proteomes; UP000268014; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR45808; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR PANTHER; PTHR45808:SF2; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000268014}.
FT DOMAIN 62..218
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT DOMAIN 245..439
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 221..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 440 AA; 50237 MW; 325CB3FBC336C340 CRC64;
MSALDRQVSA AFTEPEDGFA DDDLLTADDI SVDLSGVPPS RSFLERLDYE SELGTVDPFE
EDFSTIATHE IVEVIADGDR VGRPIIVIYA YRLPPSKSID HAKLLRYLQS ILDKVVDLDY
TIVYFHYGLR SHNKPPIKWL FQAYKVLDRR FKKNLKALYV VHPTRFIRII WGLFRPFISS
KFENKFHYVN CIRELEEALS VARLNLPQPI RTHDEQLMLG SGLASGDNRS QTPPTPPRPT
QQFGVSLEFI LSHNPDHDVP PIVTELIEFL TKHALDVEGI FRKSANVGSI RRLQERINRG
EHIDFENDPE YVDNHYVACI HASVLLKTFL RSLGEPVTTN ALYPRLAALA DVPKKEKTPA
VKEFVVLLPR PNYLLLQKVV HFLTLVAANH KVNLMTANNL SVVFGPNLTW PTDQQVPIAQ
LNNLNNFCYR LIVDYDQIFK
//
