ID   A0A0N4WFX3_HAEPC        Unreviewed;      1680 AA.
AC   A0A0N4WFX3;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=VWFA domain-containing protein {ECO:0000313|WBParaSite:HPLM_0000966201-mRNA-1};
GN   ORFNames=HPLM_LOCUS9654 {ECO:0000313|EMBL:VDO38068.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0000966201-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0000966201-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO38068.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO38068.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAF01017115; VDO38068.1; -; Genomic_DNA.
DR   STRING; 6290.A0A0N4WFX3; -.
DR   WBParaSite; HPLM_0000966201-mRNA-1; HPLM_0000966201-mRNA-1; HPLM_0000966201.
DR   OMA; GTHIVHP; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039891; VWA8.
DR   PANTHER; PTHR21610; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8; 1.
DR   PANTHER; PTHR21610:SF9; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8; 1.
DR   Pfam; PF07728; AAA_5; 3.
DR   SMART; SM00382; AAA; 3.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014}.
FT   DOMAIN          57..236
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          425..536
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          771..932
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   REGION          360..380
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1680 AA;  189053 MW;  3E6C7E88CFC41D25 CRC64;
     MRLVDVKKTV LKLGSLRVPI KETTRPELVP ARYGVHEVKV PDEALSHLKW LLQKEILGQD
     VFLIGVPGAL RSDIVLQYLE LCNREYEYLA ITRDTTESDI KQRREIRSGT AFYTDLVSTT
     AVFTVQCAVR AALHGRILVI DGVEKAERNV LPILNNLLEN REMQLDDGRF LMRPDKYDKL
     IGNYTINELR EMGIERVSER FHVIALGLPV PRFHGNSLDP PLRSRFQCRN IAEPSFEAVR
     QLCTTLAPNV NSNSINDLLS LLYAINSQPD LGLSLVPLEK AERIMRIWNI NPSYSPESMF
     NLMYPYKSMF KEHHIKVTEE FIEKFISEVG TLPTFIIVLL INNSIVSRCP LSIQRSKSSE
     PAASITRVSP SDKGTSTTVE VSFDQSRTKR TFSTEVSGKP SSEDRSFVST PSQEALLADL
     AVAHSQGDFA LLGAKGTGKT KLIAELAGRL GFNTDTMILY QDMNARELLQ RRRMLDNGDT
     LWEDSQLVAA AKRGDVCVLD GAERLPKGQL CQVHWSALES LASLCYHRTL FLPDGSRLVG
     SDEFDNIQKK TGNDEEHLNS RYGRPCHIRL LFDEIYPCFR GVFRIPKSFR LVLIGSSSLT
     ENKWLNETVI SLMPFFTMQK LSIDDQCKIL QGLVPAEASE TTRKLIEFVD KLQSSGDASL
     RGVAESLSIR KLIHIAKRDC LHPGELRDLI EKAALARFLP SVTRLAFHTE LDKAGFVKNP
     SSTDELSDDL KYLLDKNAVE DKKETMIPDV LFYENDQHMS VIRDMARDMR LGAHLLLIGN
     QGVGKNKITD RFLHLIQRPR QYMQLHRDTT VESITMQTTV ENGILRYEDS ALVRAARAGH
     VLVIDEADKA PLHVIAILKS LLDSGTLLLG DGRRIQPASA PPCDRSIPLH PDFRIIMLAN
     RPGFPFLGSP YSTYSSQLRR TVSCFLGNDL FGLLGDLFSV HTVDNPDRDS ELEMLKKYAP
     GMKLYIILCL VERGTLLLTL RDVEDGTLLK LMAAFTELRE MADEGLLQYP YSTRELVNIV
     KHVNQFPNDS LSTVIRNVFD FDAFTSDAIA TIQTVFQKHG IPFGVKRPRE HVFVSHRFPI
     EPSSSIGEWG AVDNVVPIDV KTSVASINAK AQPLKAKSLK LIKEYVRTQQ FTEQECAWQI
     PMLDVNICSD GLVLGNSLIV ATVNPTRIYV VKDLYLTDEV FEIDISSMLS HHNLLKYEPR
     IRLAQYGEGS FLVHEEVSGS ILLVDLNRNT IQRIDLGESA LSNFANRFLK SERRLVQGGC
     PLLYTREGNQ ISRFEPGGTI TQMTLGGEIS KVFPVGSDKI LVKMKSATDV IGSVKPTPSN
     VVDGRRPYYL SDDVVKKFID PYRNLIALRE GVVVRAQPKW KVPKDAAGEG RVNVHEIGGF
     LEAVNADNGF VQYIPVPEPR YHSYHGPWCA TISQTPFIIV PYNDERMLTI DTCGGVRSYE
     LSPNTLGRAF FEWNRLVGGE DDHNLRENTP HHGGNQWMGG TGGYSTAGLG GVGGPFRLDA
     GHDVHQMPDS VKKQVPDYVL KKAREVAKAE YQKRLKEIAM SEYDADAYMT FWNKIEKHSN
     HLRSIIEQLE AKKKERQWAR HQTSGDLDDG KLIEGITGER NIYRRRLDKR PEPGAPQLKP
     KRMQLCFDVS GSMYRFNGYD KRLQKSLEVA LMVMTSFEGK QEKVAVSTCT NCLVSFCTEV
//