ID A0A0N4WSD7_HAEPC Unreviewed; 385 AA.
AC A0A0N4WSD7;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Ig-like domain-containing protein {ECO:0000313|WBParaSite:HPLM_0001444501-mRNA-1};
GN ORFNames=HPLM_LOCUS14437 {ECO:0000313|EMBL:VDO52787.1};
OS Haemonchus placei (Barber's pole worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0001444501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HPLM_0001444501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO52787.1, ECO:0000313|Proteomes:UP000268014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHpl1 {ECO:0000313|EMBL:VDO52787.1,
RC ECO:0000313|Proteomes:UP000268014};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; UZAF01018567; VDO52787.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4WSD7; -.
DR STRING; 6290.A0A0N4WSD7; -.
DR WBParaSite; HPLM_0001444501-mRNA-1; HPLM_0001444501-mRNA-1; HPLM_0001444501.
DR OMA; RCNFVED; -.
DR Proteomes; UP000038042; Unplaced.
DR Proteomes; UP000268014; Unassembled WGS sequence.
DR CDD; cd00112; LDLa; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR24270:SF61; CD320 ANTIGEN; 1.
DR PANTHER; PTHR24270; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF00057; Ldl_recept_a; 3.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00409; IG; 1.
DR SMART; SM00192; LDLa; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 3.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS01209; LDLRA_1; 1.
DR PROSITE; PS50068; LDLRA_2; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Reference proteome {ECO:0000313|Proteomes:UP000268014}.
FT DOMAIN 163..259
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DISULFID 119..131
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 126..144
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 270..282
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 277..295
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 289..304
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 329..344
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 385 AA; 42371 MW; D1DE289F99A786D2 CRC64;
MLPSLYAALS LSIIYRITIN LPDLSYPTEL QNVGSESFLR TSDEIANAVN SLLVDLPGHY
NATVFQYRYH KDMGTLAYLD IYSNEMLSKK VKQRLRKAID DGFIGLDNLN TFGYANSNCP
PTEFQCSDGS CIPGSHRCNG NNDCPDGSDE RSDFAHCGHS SKPVIYQTNR VVYAPSGGVA
LLSAIIDQIP EDHQVLWSRG GKLIAEGSLT TADDSRISAY RASSEYFLRI KNVSATDEGR
YRITVSGMGA DATFELRVSA DSVKSASKNC PSNERLCRSG HCLPVSQFCD RIVQCPDGDD
EEHCTPVICS STEFRCESSN SCVPSVVRCD GWRDCHDGTD EMNCTTAGAA SQQQNHHVHH
DNHHHRKFSR LTVTCADGSP PEYSL
//
