ID   A0A0N4X2U3_HAEPC        Unreviewed;       894 AA.
AC   A0A0N4X2U3;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Myosin motor domain-containing protein {ECO:0000313|WBParaSite:HPLM_0001868501-mRNA-1};
GN   ORFNames=HPLM_LOCUS18677 {ECO:0000313|EMBL:VDO72452.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0001868501-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0001868501-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO72452.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO72452.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR   EMBL; UZAF01020731; VDO72452.1; -; Genomic_DNA.
DR   STRING; 6290.A0A0N4X2U3; -.
DR   WBParaSite; HPLM_0001868501-mRNA-1; HPLM_0001868501-mRNA-1; HPLM_0001868501.
DR   OMA; AHERFEN; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0000146; F:microfilament motor activity; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.10.820; -; 1.
DR   Gene3D; 1.20.58.530; -; 3.
DR   Gene3D; 3.40.850.10; Kinesin motor domain; 2.
DR   Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 2.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR046987; Myo9.
DR   InterPro; IPR001609; Myosin_head_motor_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR46184:SF5; HEAVY CHAIN, UNCONVENTIONAL MYOSIN; 1.
DR   PANTHER; PTHR46184; UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN; 1.
DR   Pfam; PF00063; Myosin_head; 2.
DR   Pfam; PF00788; RA; 1.
DR   PRINTS; PR00193; MYOSINHEAVY.
DR   SMART; SM00242; MYSc; 1.
DR   SMART; SM00314; RA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR   PROSITE; PS50200; RA; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00782};
KW   Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW   ProRule:PRU00782};
KW   Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW   ProRule:PRU00782};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000268014}.
FT   DOMAIN          28..134
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   DOMAIN          166..894
FT                   /note="Myosin motor"
FT                   /evidence="ECO:0000259|PROSITE:PS51456"
FT   BINDING         260..267
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ   SEQUENCE   894 AA;  102068 MW;  C591C8FA205EB4CA CRC64;
     MSFDSISSGA LGCFPRRAHT ITAPDEAHNY MVVVYMHCFN PEDQNDRVCI DLHKRSTTEE
     LIERVISLRS DLAGQSAEDF DIFEMMVTPD GQASKERRLD RGEYPVAAQL IWSRMPGGEQ
     TVNNYRFVFR HKGARTGSSC TRFGSAEAAS TIDSFLARFL QQPHDREYAD LCMLPELTEQ
     TLLDNLRDRF NSGHIYTYIG PILVAVNPFR FFPIYNPKYA RLYSQSRKLG SLPPHIFAIA
     DVTYHNMLRI KESQCVVISG ESGSGKTEST NHLISHLTSL SQKGSNACTS ETTLLNAGPV
     LEAFGNAVTL QNNNSSRFGK FIKINYRENG MVSGNYHVFY YLLEGANEED RAKYFLLKPQ
     DYHYLNQHEQ FSPEGVNEKY EFERLRRAMS SVGFNSCTQA TLFSLISAVL LLGNISYVKR
     HAYHSDENAY IENEEVVDLV AQLLNIKTEA LTQALTMKRH VMKTETVVTR YSVSEAINTR
     DAMAKCLYNA LFHWIVLRVN QALMRKDVSG SVGYYIGILD IFGFEDVGAQ WNSFEQLCIN
     YANEHLQAYF NQHIFQFEQE EYQSQGICWT NIEYTDNTEC VQLFQSKPYG LLRLIDEESN
     INNGTDESML AKLNQFLKTN EYYETPQRKE PAFIIAHYAG KVKYXINNGT DESMLAKLNQ
     FLKTNEYYET PQRKEPAFII AHYAGKVKYQ ITGFREKNKD LMRQDVLNTL KTSKCALMKA
     ALASDPVAAY RWSFARTVFR AMNAFKQSGK KLARSESAGH LRVIKEVPES RRGSDTALSQ
     FLRGDLHIDL PDFCDTSMFQ TIVNQARRTP AKGEERISTV RSLQILKETI GKRKISNKPT
     SVSKQFEFSL NRLMNTLAHA SPYFIRCIKS NNDKVSYFPV HPTIPRVFTN LHVG
//