ID A0A0N4X352_HAEPC Unreviewed; 348 AA.
AC A0A0N4X352;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=G_PROTEIN_RECEP_F3_4 domain-containing protein {ECO:0000313|WBParaSite:HPLM_0001879401-mRNA-1};
GN ORFNames=HPLM_LOCUS18786 {ECO:0000313|EMBL:VDO73212.1};
OS Haemonchus placei (Barber's pole worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0001879401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HPLM_0001879401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO73212.1, ECO:0000313|Proteomes:UP000268014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHpl1 {ECO:0000313|EMBL:VDO73212.1,
RC ECO:0000313|Proteomes:UP000268014};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; UZAF01020820; VDO73212.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4X352; -.
DR STRING; 6290.A0A0N4X352; -.
DR WBParaSite; HPLM_0001879401-mRNA-1; HPLM_0001879401-mRNA-1; HPLM_0001879401.
DR OMA; KSHESQY; -.
DR Proteomes; UP000038042; Unplaced.
DR Proteomes; UP000268014; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR PANTHER; PTHR24060:SF171; G_PROTEIN_RECEP_F3_4 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR00593; MTABOTROPICR.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 74..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 75..337
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 348 AA; 38830 MW; 7494B6BFF676D4CF CRC64;
VGKWRSSEDS FEVRVEQVRR GFRLPPGVSP YSVCSVDCPR GHYRCDMCPE GEVPDSTQSY
CVPIPPVSMQ WDSAWALVPA AFSLFGLAST TFVVGVFLKF SNTPVIMASG RELCYCMISG
ISMCYILTFF LVSQPSIPTC ALTRVLMGLS MSAIYAAIIT KTNRLARVFK PDSAQRPRFI
TPRAQVGICA CIVSVQLIGL VVWLLVDPPG TKIVFPSRTE AVLTCKATAS HLLVSLLYNL
LLIVACTVYA FKTRKIPENF NETRHIGFTM YSTCILWLSF GPIYFATQNN FRIQITSLCM
CISLSGTVAL VCFFAPKVYI VLFQPYKNVR TRQSAVGRLV NQQMRFMR
//
