ID A0A0N4X7G6_HAEPC Unreviewed; 335 AA.
AC A0A0N4X7G6;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Delta-like protein {ECO:0000256|RuleBase:RU280815};
GN ORFNames=HPLM_LOCUS20299 {ECO:0000313|EMBL:VDO82827.1};
OS Haemonchus placei (Barber's pole worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0002030801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HPLM_0002030801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO82827.1, ECO:0000313|Proteomes:UP000268014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHpl1 {ECO:0000313|EMBL:VDO82827.1,
RC ECO:0000313|Proteomes:UP000268014};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Putative Notch ligand involved in the mediation of Notch
CC signaling. {ECO:0000256|RuleBase:RU280815}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280815}; Single-
CC pass type I membrane protein {ECO:0000256|RuleBase:RU280815}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00377}.
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DR EMBL; UZAF01022060; VDO82827.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4X7G6; -.
DR STRING; 6290.A0A0N4X7G6; -.
DR WBParaSite; HPLM_0002030801-mRNA-1; HPLM_0002030801-mRNA-1; HPLM_0002030801.
DR OMA; LENWINQ; -.
DR Proteomes; UP000038042; Unplaced.
DR Proteomes; UP000268014; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR Gene3D; 2.10.25.140; -; 1.
DR InterPro; IPR001774; DSL.
DR InterPro; IPR000742; EGF-like_dom.
DR Pfam; PF01414; DSL; 1.
DR SMART; SM00051; DSL; 1.
DR PROSITE; PS51051; DSL; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|RuleBase:RU280815};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00377}; EGF-like domain {ECO:0000256|RuleBase:RU280815};
KW Membrane {ECO:0000256|RuleBase:RU280815, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU280815};
KW Signal {ECO:0000256|RuleBase:RU280815};
KW Transmembrane {ECO:0000256|RuleBase:RU280815, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|RuleBase:RU280815,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 85..127
FT /note="DSL"
FT /evidence="ECO:0000259|PROSITE:PS51051"
FT REGION 216..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 87..96
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00377"
FT DISULFID 118..127
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00377"
SQ SEQUENCE 335 AA; 36429 MW; 9ECEB12C79A30BA4 CRC64;
MLPYPIKDPD RKCLKSGQLE IVGGTETVLD LIITNITVEY ITVEFEIVGN TERPIQRISK
RIAVDGGLPA ERVAVAKGIL IDFVTKCTRP FYGIMCARQC FEEDGAKYVC DPHGEKVCLV
GWTGKDCNTG KCRLSLAFDV ICLCLVGWTG KDCNTAMTGV STEKLSSHAP ILTSTSTSHK
VDLSSHAPIL TTTSSGRLLT KDIETTTRPK VLLVDPDVQK PSTPSPVATK QLPEKPVSAG
PLSTGSTPVA HMTAVPTSTS RVTALPANSL IDHVLVLFFV AMLIGVIKYA TWKMTRSVLL
ENWINQKRAK VFTTESSSHS LRKDVTEKVR AGYHS
//
